Glycoengineered antibody drug conjugates

LZ Avila, Q Zhou - US Patent 10,064,952, 2018 - Google Patents
US10064952B2 - Glycoengineered antibody drug conjugates - Google Patents
US10064952B2 - Glycoengineered antibody drug conjugates - Google Patents …

Site-specific antibody-drug conjugation through glycoengineering

C Pan, Q Zhou, J Stefano, P Dhal, B Chen… - US Patent …, 2019 - Google Patents
US10214589B2 - Site-specific antibody-drug conjugation through glycoengineering -
Google Patents US10214589B2 - Site-specific antibody-drug conjugation through …

Fc containing polypeptides with altered glycosylation and reduced effector function

C Pan, H Qiu - US Patent 10,836,813, 2020 - Google Patents
Int. Cl. C07H 21/02(2006.01) CO7H 21/04(2006.01) C12N 5/02(2006.01) C12N
5/16(2006.01) C12N 1/20(2006.01) C12N 15/00(2006.01) C12P 21/06(2006.01) C12P …

Anti-αβTCR antibody

D Snell, A Menrad, G Lacorcia, S Shankara… - US Patent …, 2021 - Google Patents
US11186638B2 - Anti-αβTCR antibody - Google Patents US11186638B2 - Anti-αβTCR antibody
- Google Patents Anti-αβTCR antibody Download PDF Info Publication number US11186638B2 …

Hyperglycosylated binding polypeptides

C Pan, H Qiu, P Dhal, B Chen, D Gianolio - US Patent 10,494,439, 2019 - Google Patents
Provided are binding polypeptides (eg, antibodies), and effector moiety conjugates thereof,
comprising a CH1 domain (eg, a human IgG1 CH1 domain), wherein the CH1 domain has …

Glycoengineered antibody drug conjugates

LZ Avila, Q Zhou - US Patent 11,160,874, 2021 - Google Patents
VBHXIZLOROMSTN-UHFFFAOYSA-N C. CC (= O) NC1C (O) CC (C)(OC (C) P) OC1C (O)
C= O. CC (= O) NC1C (O) CC (OC (C) P)(C (= O) O) OC1C= O Chemical compound C. CC …

Site-specific antibody-drug conjugation through glycoengineering

C Pan, Q Zhou, J Stefano, P Dhal, B Chen… - US Patent …, 2021 - Google Patents
The current disclosure provides binding polypeptides (eg, antibodies), and effector moiety
conjugates thereof (eg, antibody-drug conjugates or ADCs), comprising a site specifically …

Hyperglycosylated binding polypeptides

C Pan, H Qiu, P Dhal, B Chen, D Gianolio - US Patent 11,807,690, 2023 - Google Patents
A61K47/50—Medicinal preparations characterised by the non-active ingredients used, eg
carriers or inert additives; Targeting or modifying agents chemically bound to the active …

Antibodies against LIF and uses thereof

JS Suarez, JA Folgueira - US Patent 10,583,191, 2020 - Google Patents
US10583191B2 - Antibodies against LIF and uses thereof - Google Patents
US10583191B2 - Antibodies against LIF and uses thereof - Google Patents Antibodies …

Antibodies against LIF and uses thereof

JS Suarez, JA Folgueira - US Patent 10,206,999, 2019 - Google Patents
US10206999B2 - Antibodies against LIF and uses thereof - Google Patents
US10206999B2 - Antibodies against LIF and uses thereof - Google Patents Antibodies …