Osteoarthritis (OA) is a heterogeneous disorder with several risk factors. Among them,
obesity has a major impact on both loading and non-loading joints. Mechanical overload …

Osteosarcopenic obesity (OSO) syndrome describes the simultaneous deterioration of bone,
muscle and excess fat, resulting in reduced functionality and systemic metabolic …

Importance Treatment of pediatric obesity is challenging. Preclinical studies in mice
indicated that weight and metabolism can be altered by gut microbiome manipulation …

Context Glucagon-like peptide-1 receptor agonists and sodium-glucose cotransporter-2
inhibitors reduce weight and improve insulin sensitivity via different mechanisms. Objective …

Objective To study the efficacy and safety of the GLP-1 analog liraglutide 3 mg (LIRA 3 mg)
vs. placebo (PL) for reduction of body weight (BW) and hyperandrogenism in women with …

The concept of heterogeneity among obese individuals in their risk for developing metabolic
dysfunction and associated complications has been recognized for decades. At the origin of …

Background The relation between socioeconomic position (SEP) and obesity measured by
body mass index (BMI), a measure of weight for height, has been extensively reviewed in …

Immune cells are an inseparable component of adipose tissue intimately involved in most of
its functions. Physiologically, they regulate adipose tissue homeostasis, while in case of …

Introduction Multiple systematic reviews have investigated the relation between
socioeconomic position (SEP) and body mass index (BMI) throughout the life course …

Background & aims Previous studies linking the gut microbiome with childhood obesity
largely used the body mass index to measure obesity and reached inconsistent findings …