Gut-liver axis: Pathophysiological concepts and clinical implications
H Tilg, TE Adolph, M Trauner - Cell metabolism, 2022 - cell.com
Bidirectional crosstalk along the gut-liver axis controls gastrointestinal health and disease
and exploits environmental and host mediators. Nutrients, microbial antigens, metabolites …
and exploits environmental and host mediators. Nutrients, microbial antigens, metabolites …
Advances in the diagnosis and treatment of non-alcoholic fatty liver disease
X Yin, X Guo, Z Liu, J Wang - International Journal of Molecular Sciences, 2023 - mdpi.com
Non-alcoholic fatty liver disease (NAFLD) is the most prevalent chronic liver disease that
affects approximately one-quarter of the global adult population, posing a significant threat …
affects approximately one-quarter of the global adult population, posing a significant threat …
Tumour extracellular vesicles and particles induce liver metabolic dysfunction
Cancer alters the function of multiple organs beyond those targeted by metastasis,. Here we
show that inflammation, fatty liver and dysregulated metabolism are hallmarks of …
show that inflammation, fatty liver and dysregulated metabolism are hallmarks of …
MASLD: a systemic metabolic disorder with cardiovascular and malignant complications
Non-alcoholic fatty liver disease (NAFLD) has rapidly become the most common chronic
liver disease globally and is currently estimated to affect up to 38% of the global adult …
liver disease globally and is currently estimated to affect up to 38% of the global adult …
Non-alcoholic fatty liver disease: pathophysiological concepts and treatment options
C Grander, F Grabherr, H Tilg - Cardiovascular Research, 2023 - academic.oup.com
The prevalence of non-alcoholic fatty liver disease (NAFLD) is continually increasing due to
the global obesity epidemic. NAFLD comprises a systemic metabolic disease accompanied …
the global obesity epidemic. NAFLD comprises a systemic metabolic disease accompanied …
Orosomucoid 2 maintains hepatic lipid homeostasis through suppression of de novo lipogenesis
B Zhou, Y Luo, N Ji, C Hu, Y Lu - Nature Metabolism, 2022 - nature.com
Non-alcoholic fatty liver disease (NAFLD) is caused by imbalance in lipid metabolism. In this
study, we show that the hepatokine orosomucoid (ORM) 2 is a key regulator of de novo …
study, we show that the hepatokine orosomucoid (ORM) 2 is a key regulator of de novo …
Association between non-alcoholic fatty liver disease and heavy metal exposure: a systematic review
P Sadighara, AH Abedini, N Irshad… - Biological trace element …, 2023 - Springer
Non-alcoholic fatty liver disease (NAFLD) is a debilitating disease with adverse effects
including cirrhosis and hepatocellular carcinoma. Heavy metals can cause severe …
including cirrhosis and hepatocellular carcinoma. Heavy metals can cause severe …
NASH drug treatment development: challenges and lessons
Non-alcoholic fatty liver disease (NAFLD) has become the most common chronic liver
disease worldwide. Although NAFLD is tightly linked to obesity and type 2 diabetes, this liver …
disease worldwide. Although NAFLD is tightly linked to obesity and type 2 diabetes, this liver …
Targeted modulation of gut microbiota by traditional Chinese medicine and natural products for liver disease therapy
LR Zhu, SS Li, WQ Zheng, WJ Ni, M Cai… - Frontiers in …, 2023 - frontiersin.org
The gut microbiota not only constitutes intestinal microenvironment homeostasis and human
health but also exerts indispensable roles in the occurrence and progression of multiple liver …
health but also exerts indispensable roles in the occurrence and progression of multiple liver …
Efficacy and safety of dietary polyphenol supplementation in the treatment of non-alcoholic fatty liver disease: A systematic review and meta-analysis
K Yang, J Chen, T Zhang, X Yuan, A Ge… - Frontiers in …, 2022 - frontiersin.org
Background Dietary polyphenol treatment of non-alcoholic fatty liver disease (NAFLD) is a
novel direction, and the existing clinical studies have little effective evidence for its …
novel direction, and the existing clinical studies have little effective evidence for its …