Consensus guidelines for the use and interpretation of angiogenesis assays

P Nowak-Sliwinska, K Alitalo, E Allen, A Anisimov… - Angiogenesis, 2018 - Springer
The formation of new blood vessels, or angiogenesis, is a complex process that plays
important roles in growth and development, tissue and organ regeneration, as well as …

Regulation of placental development and its impact on fetal growth—new insights from mouse models

L Woods, V Perez-Garcia, M Hemberger - Frontiers in endocrinology, 2018 - frontiersin.org
The placenta is the chief regulator of nutrient supply to the growing embryo during gestation.
As such, adequate placental function is instrumental for developmental progression …

Blood flow forces in shaping the vascular system: a focus on endothelial cell behavior

P Campinho, A Vilfan, J Vermot - Frontiers in physiology, 2020 - frontiersin.org
The endothelium is the cell monolayer that lines the interior of the blood vessels separating
the vessel lumen where blood circulates, from the surrounding tissues. During embryonic …

Building and regenerating the lung cell by cell

JA Whitsett, TV Kalin, Y Xu… - Physiological …, 2019 - journals.physiology.org
The unique architecture of the mammalian lung is required for adaptation to air breathing at
birth and thereafter. Understanding the cellular and molecular mechanisms controlling its …

FOXF1 transcription factor is required for formation of embryonic vasculature by regulating VEGF signaling in endothelial cells

X Ren, V Ustiyan, A Pradhan, Y Cai… - Circulation …, 2014 - Am Heart Assoc
Rationale: Inactivating mutations in the Forkhead Box transcription factor F1 (FOXF1) gene
locus are frequently found in patients with alveolar capillary dysplasia with misalignment of …

State-of-the-art methods for evaluation of angiogenesis and tissue vascularization: a scientific statement from the American Heart Association

M Simons, K Alitalo, BH Annex, HG Augustin… - Circulation …, 2015 - Am Heart Assoc
The American Heart Association makes every effort to avoid any actual or potential conflicts
of interest that may arise as a result of an outside relationship or a personal, professional, or …

Embryonic and extraembryonic tissues during mammalian development: shifting boundaries in time and space

S Thowfeequ, S Srinivas - Philosophical Transactions of …, 2022 - royalsocietypublishing.org
The first few days of embryonic development in eutherian mammals are dedicated to the
specification and elaboration of the extraembryonic tissues. However, where the fetus ends …

Rewiring of embryonic glucose metabolism via suppression of PFK-1 and aldolase during mouse chorioallantoic branching

H Miyazawa, Y Yamaguchi, Y Sugiura… - …, 2017 - journals.biologists.com
Adapting the energy metabolism state to changing bioenergetic demands is essential for
mammalian development accompanying massive cell proliferation and cell differentiation …

Mouse placenta fetal macrophages arise from endothelial cells outside the placenta

X Chen, AT Tang, J Tober, J Yang, NA Leu, S Sterling… - Developmental cell, 2022 - cell.com
Placental fetal macrophages (fMacs) are the only immune cells on the fetal side of the
placental barrier. Mouse models have not been used to test their function because they have …

Transcription factors regulating embryonic development of pulmonary vasculature

C Bolte, JA Whitsett, TV Kalin… - Molecular and Functional …, 2018 - Springer
Lung morphogenesis is a highly orchestrated process beginning with the appearance of
lung buds on approximately embryonic day 9.5 in the mouse. Endodermally derived …