[HTML][HTML] Exploring lncRNA-mediated regulatory networks in endometrial cancer cells and the tumor microenvironment: advances and challenges
P Dong, Y Xiong, J Yue, S JB Hanley, N Kobayashi… - Cancers, 2019 - mdpi.com
Recent studies have revealed both the promise and challenges of targeting long non-coding
RNAs (lncRNAs) to diagnose and treat endometrial cancer (EC). LncRNAs are upregulated …
RNAs (lncRNAs) to diagnose and treat endometrial cancer (EC). LncRNAs are upregulated …
[HTML][HTML] The impact of microRNA-mediated PI3K/AKT signaling on epithelial-mesenchymal transition and cancer stemness in endometrial cancer
P Dong, Y Konno, H Watari, M Hosaka… - Journal of translational …, 2014 - Springer
Activation of the PI3K/AKT pathway, a common mechanism in all subtypes of endometrial
cancers (endometrioid and non-endometrioid tumors), has important roles in contributing to …
cancers (endometrioid and non-endometrioid tumors), has important roles in contributing to …
[HTML][HTML] MicroRNA-101 targets EZH2, MCL-1 and FOS to suppress proliferation, invasion and stem cell-like phenotype of aggressive endometrial cancer cells
Y Konno, P Dong, Y Xiong, F Suzuki, J Lu, M Cai… - Oncotarget, 2014 - ncbi.nlm.nih.gov
MicroRNA-101 has been implicated as a tumor suppressor miRNA in human tumors.
However, its potential functional impact and the underlying mechanisms in endometrial …
However, its potential functional impact and the underlying mechanisms in endometrial …
[HTML][HTML] EZH2 inhibition suppresses endometrial cancer progression via miR-361/Twist axis
K Ihira, P Dong, Y Xiong, H Watari, Y Konno… - Oncotarget, 2017 - ncbi.nlm.nih.gov
EZH2 inhibition and reactivation of tumor suppressor microRNAs (miRNAs) represent
attractive anti-cancer therapeutic strategies. We found that EZH2-suppressed let 7b and miR …
attractive anti-cancer therapeutic strategies. We found that EZH2-suppressed let 7b and miR …
miR-214-3p inhibits epithelial-to-mesenchymal transition and metastasis of endometrial cancer cells by targeting TWIST1
YY Fang, MR Tan, J Zhou, L Liang, XY Liu… - OncoTargets and …, 2019 - Taylor & Francis
Background Substantive studies have described the ectopic microRNAs as a determinant of
the pathogenesis of endometrial cancer (EC). miR-214-3p has been reported to be …
the pathogenesis of endometrial cancer (EC). miR-214-3p has been reported to be …
[HTML][HTML] Long non-coding RNA TMPO-AS1 promotes GLUT1-mediated glycolysis and paclitaxel resistance in endometrial cancer cells by interacting with miR-140 and …
Increased glycolysis in tumor cells is frequently associated with drug resistance.
Overexpression of glucose transporter-1 (GLUT1) promotes the Warburg effect and …
Overexpression of glucose transporter-1 (GLUT1) promotes the Warburg effect and …
[HTML][HTML] MicroRNA as epigenetic modifiers in endometrial cancer: a systematic review
A Favier, G Rocher, AK Larsen, R Delangle, C Uzan… - Cancers, 2021 - mdpi.com
Simple Summary Endometrial cancer (EC) is the 2nd most common gynecologic cancer
worldwide. MicroRNAs (miRNAs) are small noncoding RNAs that contribute to epigenetic …
worldwide. MicroRNAs (miRNAs) are small noncoding RNAs that contribute to epigenetic …
[HTML][HTML] MicroRNA-134 suppresses endometrial cancer stem cells by targeting POGLUT1 and Notch pathway proteins
Y Gao, T Liu, Y Huang - FEBS letters, 2015 - Elsevier
We aimed to ascertain the role of microRNAs (miRNAs) in regulating human endometrial
cancer stem cells (HuECSCs). The expression level of miRNA-134 (miR-134), a member of …
cancer stem cells (HuECSCs). The expression level of miRNA-134 (miR-134), a member of …
[HTML][HTML] miR-34a, miR-424 and miR-513 inhibit MMSET expression to repress endometrial cancer cell invasion and sphere formation
P Dong, Y Xiong, J Yue, SJB Hanley, H Watari - Oncotarget, 2018 - ncbi.nlm.nih.gov
Although the oncogene MMSET (also known as NSD2 or WHSC1) has an essential role in
malignancies, its impact on human endometrial cancer (EC) metastasis and the molecular …
malignancies, its impact on human endometrial cancer (EC) metastasis and the molecular …
Hsa-microRNA-181a is a regulator of a number of cancer genes and a biomarker for endometrial carcinoma in patients: a bioinformatic and clinical study and the …
S He, S Zeng, ZW Zhou, ZX He… - Drug design, development …, 2015 - Taylor & Francis
The aberrant expression of human microRNA-181a-1 (hsa-miR-181a) has been implicated
in the pathogenesis of various cancers, serving as an oncogene or a tumor suppressor …
in the pathogenesis of various cancers, serving as an oncogene or a tumor suppressor …