BACKGROUND Male infertility affects> 20 million men worldwide and represents a major
health concern. Although multifactorial, male infertility has a strong genetic basis which has …

DNA damage is frequently encountered in spermatozoa of subfertile males and is correlated
with a range of adverse clinical outcomes including impaired fertilization, disrupted …

Background: Primary infertility is a serious health issue that has profound socioeconomic
and health implications on both the individual and society. Despite the important …

Fertility in the male is dependent on the proper production of sperm cells. This process,
called spermatogenesis is very complex and involves the synchronization of numerous …

BACKGROUND Mammalian oocytes are activated by intracellular calcium (Ca2+)
oscillations following gamete fusion. Recent evidence implicates a sperm-specific …

Establishment of spermatogonia throughout the fetal and postnatal period is essential for
production of spermatozoa and male fertility. Here, we establish a protocol for in vitro …

Individuals who smoke generally do so with the knowledge of potential consequences to
their own health. What is rarely considered are the effects of smoking on their future children …

Spermatogonial stem cells (SSCs) fuel the production of male germ cells but the
mechanisms behind SSC self-renewal, proliferation, and differentiation are still poorly …

Sperm motility is the major decisive factor in determining male fertility. The objective of the
present study was to analyse the effect of mitochondrial membrane potential (MMP) on the …

Objective To investigate the expression profiles of microRNA (miRNA) in human testes
showing different histopathological patterns. Design Microarray with quantitative real-time …