Polyploidy has been hypothesized to be both an evolutionary dead-end and a source for
evolutionary innovation and species diversification. Although polyploid organisms …

Transcription factors (TFs) recognize specific DNA sequences to control chromatin and
transcription, forming a complex system that guides expression of the genome. Despite keen …

Artificial intelligence-based protein structure prediction methods such as AlphaFold have
revolutionized structural biology. The accuracies of these predictions vary, however, and …

Polyploidy, or the duplication of entire genomes, has been observed in prokaryotic and
eukaryotic organisms, and in somatic and germ cells. The consequences of polyploidization …

Although it is widely believed that early vertebrate evolution was shaped by ancient whole-
genome duplications, the number, timing and mechanism of these events remain elusive …

Ancient duplication events and a high rate of retention of extant pairs of duplicate genes
have contributed to an abundance of duplicate genes in plant genomes. These duplicates …

Background The sharp increase of plant genome and transcriptome data provide valuable
resources to investigate evolutionary consequences of gene duplication in a range of taxa …

Ancient polyploidization events have had a lasting impact on vertebrate genome structure,
organization and function. Some key questions regarding the number of ancient …

Our understanding of phylogenetic relationships among bony fishes has been transformed
by analysis of a small number of genes, but uncertainty remains around critical nodes …

To connect human biology to fish biomedical models, we sequenced the genome of spotted
gar (Lepisosteus oculatus), whose lineage diverged from teleosts before teleost genome …