Preterm birth is associated with a high risk of morbidity and mortality including brain damage
and cerebral palsy. The development of brain injury in the preterm infant may be influenced …

Free radicals play a role of paramount importance in the development of neonatal brain
injury. Depending on the pathophysiological mechanisms underlying free radical …

Objective Hypoxic-ischaemic encephalopathy (HIE) remains a leading cause of neonatal
mortality and neurodisability. We aimed to determine the incidence of HIE and management …

Background Infants with mild HIE are at risk of significant disability at follow-up. In the pre-
therapeutic hypothermia (TH) era, electroencephalography (EEG) within 6 hours of birth was …

Context: Several interventions are available for the management of hypoxic ischemic
encephalopathy (HIE), but no studies have compared their relative efficacy in a single …

Therapeutic hypothermia (TH) is standard treatment for neonates (≥ 36 weeks) with
perinatal asphyxia (PA) and hypoxic–ischemic encephalopathy. TH reduces mortality and …

The survival of preterm infants has steadily improved thanks to advances in perinatal and
neonatal intensive clinical care. The focus is now on finding ways to improve morbidities …

Neonatal hypoxic ischemia (HI) results in different extents of brain damage, and immature
brain tissue is particularly sensitive to the stimulation of HI. Hypoxic-ischemic brain damage …

Hypoxic-ischemic encephalopathy is a subtype of neonatal encephalopathy and a major
contributor to global neonatal morbidity and mortality. Despite advances in obstetric and …

Objective To test the inter-rater reliability of the modified Sarnat neurologic examination in
preterm neonates and to correlate abnormalities with the presence of perinatal acidosis …