Diabetes mellitus and its metabolic complications: the role of adipose tissues

L Dilworth, A Facey, F Omoruyi - International journal of molecular …, 2021 - mdpi.com
Many approaches have been used in the effective management of type 2 diabetes mellitus.
A recent paradigm shift has focused on the role of adipose tissues in the development and …

Effects of diet, lifestyle, chrononutrition and alternative dietary interventions on postprandial glycemia and insulin resistance

E Papakonstantinou, C Oikonomou, G Nychas… - Nutrients, 2022 - mdpi.com
As years progress, we are found more often in a postprandial than a postabsorptive state.
Chrononutrition is an integral part of metabolism, pancreatic function, and hormone …

Sex differences in body composition

MA Bredella - Sex and gender factors affecting metabolic …, 2017 - Springer
Body composition differs between men and women. Men have more lean mass, and women
have more fat mass than men. Men are more likely to accumulate adipose tissue around the …

The lifecycle of skeletal muscle mitochondria in obesity

CA Pileggi, G Parmar, ME Harper - Obesity Reviews, 2021 - Wiley Online Library
Skeletal muscle possesses dramatic metabolic plasticity that allows for the rapid adaptation
in cellular energy transduction to meet the demands of the organism. Obesity elicits changes …

Sarcopenia: an undiagnosed condition in older adults. Current consensus definition: prevalence, etiology, and consequences. International working group on …

RA Fielding, B Vellas, WJ Evans, S Bhasin… - Journal of the American …, 2011 - Elsevier
Sarcopenia, the age-associated loss of skeletal muscle mass and function, has considerable
societal consequences for the development of frailty, disability, and health care planning. A …

Acylcarnitines: reflecting or inflicting insulin resistance?

MG Schooneman, FM Vaz, SM Houten, MR Soeters - Diabetes, 2013 - Am Diabetes Assoc
The incidence of obesity and insulin resistance is growing, and the increase in type 2
diabetes mel-litus (DM2) constitutes one of the biggest challenges for our healthcare …

Advances in understanding of the role of lipid metabolism in aging

KW Chung - Cells, 2021 - mdpi.com
During aging, body adiposity increases with changes in the metabolism of lipids and their
metabolite levels. Considering lipid metabolism, excess adiposity with increased lipotoxicity …

Moderate-intensity exercise and high-intensity interval training affect insulin sensitivity similarly in obese adults

BJ Ryan, MW Schleh, C Ahn, AC Ludzki… - The Journal of …, 2020 - academic.oup.com
Objective We compared the effects of high-intensity interval training (HIIT) and moderate-
intensity continuous training (MICT) on insulin sensitivity and other important metabolic …

Obesity in type 1 diabetes: pathophysiology, clinical impact, and mechanisms

KD Corbin, KA Driscoll, RE Pratley, SR Smith… - Endocrine …, 2018 - academic.oup.com
There has been an alarming increase in the prevalence of obesity in people with type 1
diabetes in recent years. Although obesity has long been recognized as a major risk factor …

Muscle mass index as a predictor of longevity in older adults

P Srikanthan, AS Karlamangla - The American journal of medicine, 2014 - Elsevier
Objective Obesity (as defined by body mass index) has not been associated consistently
with higher mortality in older adults. However, total body mass includes fat and muscle …