• The specific situation of the patient. Unless otherwise provided for by national regulations,
off-label use of medication should be limited to situations where it is in the patient's interest …

Background Frailty is emerging as an important prognostic indicator for patients undergoing
cardiac surgeries/procedures. We sought to evaluate the prognostic and differential impacts …

The incidence of infective endocarditis (IE) has increased globally in the past decades,
including in the United States. However, little is known about the differences in trends across …

Purpose: This study explored the sex differences in the outcomes of degenerative mitral
valve repair (MVr). Methods: From 2010 to 2019, 1069 patients who underwent MVr due to …

Background Transcatheter aspiration is utilized for removal of thrombi and vegetations in
inoperable patients and high-risk surgical candidates where medical therapy alone is …

Despite the advancement in medicine, there is still a lack of understanding of the sex
disparities in disease onset, progression, treatment, and outcome. In some life-threatening …

Approximately a quarter of patients with infective endocarditis (IE) who have surgical
indication only receive antibiotic treatment. Their short-term prognosis is dismal. We aimed …

Background The incidence of infective endocarditis (IE) is rapidly increasing. Contemporary
outcomes following high-risk double valve surgery (DVS) for IE are not well described …

Background Outcomes after transcatheter aortic valve replacement (TAVR) and infectious
diseases may vary according to sex. Methods This multicentre study aimed to determine the …

Purpose Sex differences in infective endocarditis (IE) are reported, but patient characteristics
are sparse and conflicting findings on the association between sex and short-term outcomes …