Growth and differentiation factor 15 (GDF15) is a member of the transforming growth factor‐β
(TGF‐β) superfamily. GDF15 has been linked with several metabolic syndrome pathologies …

Pyroptosis, an inflammatory programmed cell death, distinguishes itself from apoptosis and
necroptosis and has drawn increasing attention. Recent studies have revealed a correlation …

Objective Revealing the single-cell immune ecosystems in true versus de novo
hepatocellular carcinoma (HCC) recurrences could help the optimal development of …

Exercise is a first-line treatment for type 2 diabetes and preserves β-cell function by hitherto
unknown mechanisms. We postulated that proteins from contracting skeletal muscle may act …

Simple Summary OV is the most lethal gynecological malignancy. M6A and lncRNAs have a
great impact on OV development and patient immunotherapy response. This study provided …

Background Immunotherapy brings new hope to patients with advanced gastric cancer.
However, liver metastases can reduce the efficacy of immunotherapy in patients. Tumor …

The Nicoya OpenSPR is a benchtop surface plasmon resonance (SPR) instrument. As with
other optical biosensor instruments, it is suitable for the label-free interaction analysis of a …

Despite technological advances in diagnostic abilities and improved treatment methods, the
burden of cancers remains high, leading to significant morbidity and mortality. One primary …

Introduction Current treatment for type 1 diabetes (T1D) is centered around insulin
supplementation to manage the effects of pancreatic β cell loss. GDF15 is a potential …

As one of the most successful cancer therapeutic targets, estrogen receptor-α (ER/ESR1)
has been extensively studied over the past few decades. Sequencing technological …