We abtained normative data for plasma renin activity (PRA) and plasma aldosterone
concentration from a biracial sample of 195 healthy, normotensive children and adolescents …

In a Caribbean outbred population of African green monkeys (Cercopithecus aethiops), 5 to
10% of feral adults have elevated blood pressure (BP). We have investigated whether the …

Pioneer studies have proposed that multiple metabolic abnormalities, such as insulin
resistance, increased Na+-H+ exchanger activity and abnormal intracellular calcium …

The renin-angiotensin system (RAS) plays a key role in a number of pathophysiological
mechanisms that are involved in the development and progression of cardiovascular and …

Nonmodulation is a process in which there is a disorder in angiotensin-dependent control of
the renal circulation and adrenal aldosterone release. The abnormalities are associated with …

Objective. It has been previously demonstrated that structural alterations of subcutaneous
small resistance arteries of hypertensive patients, as indicated by an increased media to …

Several studies have shown an inverse relation between blood pressure and plasma
aldosterone levels. Since blood pressure is in part genetically regulated, we looked for …

A case of familial elevation of plasma prorenin levels was discovered during an
epidemiological survey of a Dutch population. Trypsin-activated prorenin was elevated in …

Offspring hypertensives are characterized by a hyperactive sympathetic nervous system and
other early cardiovascular abnormalities that increase the risk of developing hypertension. A …

1. The SA gene is expressed in the kidneys and is associated with hypertension in man and
experimental animal models. Predisposition to hypertension is associated with renal …