Recent updates on 1, 2, 3-triazole-containing hybrids with in vivo therapeutic potential against cancers: A mini-review

S Zhao, J Liu, Z Lv, G Zhang, Z Xu - European Journal of Medicinal …, 2023 - Elsevier
Triazole moiety which is usually constructed by highly versatile, efficacious and selective
copper-catalyzed azide-alkyne cycloaddition not only can act as a linker to connect different …

The 1, 2, 3-triazole 'all-in-one'ring system in drug discovery: A good bioisostere, a good pharmacophore, a good linker, and a versatile synthetic tool

D Lengerli, K Ibis, Y Nural… - Expert opinion on drug …, 2022 - Taylor & Francis
ABSTRACT Introduction The 1, 2, 3-triazole ring occupies an important space in medicinal
chemistry due to its unique structural properties, synthetic versatility and pharmacological …

[HTML][HTML] The fate of heterogeneous catalysis & click chemistry for 1, 2, 3-triazoles: Nobel prize in chemistry 2022

V Kumar, K Lal, RK Tittal - Catalysis Communications, 2023 - Elsevier
The demand for environmental friendly methodologies had shifted the the approach of
scientific community for using easy and green reaction conditions instead of using …

Recent progress in 1H-1, 2, 3-triazoles as potential antifungal agents

N Poonia, A Kumar, V Kumar… - Current Topics in …, 2021 - ingentaconnect.com
The need to overcome ever-increasing cases of antifungal resistance and circumvent side
effects and drug interactions related to currently available drugs has impelled the demand to …

Emerging impact of triazoles as anti-tubercular agent

A Sharma, AK Agrahari, S Rajkhowa… - European Journal of …, 2022 - Elsevier
Tuberculosis, a disease of poverty is a communicable infection with a reasonably high
mortality rate worldwide. 10 Million new cases of TB were reported with approx 1.4 million …

1, 2, 3-Triazole-containing hybrids with potential antibacterial activity against ESKAPE pathogens

C Deng, H Yan, J Wang, K Liu, B Liu, Y Shi - European Journal of …, 2022 - Elsevier
ESKAPE pathogens, as priority 1 and 2 pathogens, are prevalent infectious agents
associated with high morbidity and mortality. ESKAPE can cause broad-spectrum diseases …

Synthesis, characterization, molecular docking and in vitro anti-cancer activity studies of new and highly selective 1, 2, 3-triazole substituted 4-hydroxybenzohyrdazide …

H Şenol, AG Ağgül, S Atasoy… - Journal of Molecular …, 2023 - Elsevier
In this study, 16 new hybrid compounds 6 (ah) and 7 (ah) were synthesized starting from
methylparaben. These new compounds consist of eight 1, 2, 3-triazole-arylidenehydrazide …

Recent advances in bioactive flavonoid hybrids linked by 1, 2, 3-triazole ring obtained by click chemistry

D Pereira, M Pinto, M Correia-da-Silva, H Cidade - Molecules, 2021 - mdpi.com
As a result of the biological activities of natural flavonoids, several synthetic strategies
aiming to obtain analogues with improved potency and/or pharmacokinetic profile have …

Recent progress in catalytic synthesis of 1, 2, 3-triazoles

A De Nino, L Maiuolo, P Costanzo, V Algieri, A Jiritano… - Catalysts, 2021 - mdpi.com
1, 2, 3-triazoles represent a functional heterocyclic core that has been at the center of
modern organic chemistry since the beginning of click chemistry. Being a versatile …

The antibacterial activity of 1, 2, 3-triazole-and 1, 2, 4-triazole-containing hybrids against Staphylococcus aureus: An updated review (2020-present)

J Li, J Zhang - Current Topics in Medicinal Chemistry, 2022 - ingentaconnect.com
Staphylococcus aureus (S. aureus), a prominent, highly contagious nosocomial and
community-acquired bacterial pathogen, can cause a broad spectrum of diseases. Antibiotic …