[HTML][HTML] The epigenetic regulatory mechanism of PIWI/piRNAs in human cancers

Q Zhang, Y Zhu, X Cao, W Tan, J Yu, Y Lu, R Kang… - Molecular Cancer, 2023 - Springer
PIWI proteins have a strong correlation with PIWI-interacting RNAs (piRNAs), which are
significant in development and reproduction of organisms. Recently, emerging evidences …

[PDF][PDF] PIWI proteins and PIWI-interacting RNA: emerging roles in cancer

YN Han, Y Li, SQ Xia, YY Zhang, JH Zheng… - Cellular Physiology and …, 2018 - karger.com
P-Element induced wimpy testis (PIWI)-interacting RNAs (piRNAs) are a type of noncoding
RNAs (ncRNAs) and interact with PIWI proteins. piRNAs were primarily described in the …

[HTML][HTML] LncRNA MT1JP functions as a ceRNA in regulating FBXW7 through competitively binding to miR-92a-3p in gastric cancer

G Zhang, S Li, J Lu, Y Ge, Q Wang, G Ma, Q Zhao… - Molecular cancer, 2018 - Springer
Background Emerging evidence has shown that dysregulation function of long non-coding
RNAs (lncRNAs) implicated in gastric cancer (GC). However, the role of the differentially …

piRBase: a comprehensive database of piRNA sequences

J Wang, P Zhang, Y Lu, Y Li, Y Zheng… - Nucleic acids …, 2019 - academic.oup.com
PIWI-interacting RNAs are a class of small RNAs that is most abundantly expressed in
animal germline. Substantial research is going on to reveal the functions of piRNAs in the …

piRBase: integrating piRNA annotation in all aspects

J Wang, Y Shi, H Zhou, P Zhang, T Song… - Nucleic acids …, 2022 - academic.oup.com
Piwi-interacting RNAs are a type of small noncoding RNA that have various functions.
piRBase is a manually curated resource focused on assisting piRNA functional analysis …

[HTML][HTML] PIWI-interacting RNA-36712 restrains breast cancer progression and chemoresistance by interaction with SEPW1 pseudogene SEPW1P RNA

L Tan, D Mai, B Zhang, X Jiang, J Zhang, R Bai, Y Ye… - Molecular cancer, 2019 - Springer
Background Breast cancer is one of the most common malignancies and the major cause of
cancer-related death in women. Although the importance of PIWI-interacting RNAs (piRNAs) …

[HTML][HTML] The biogenesis and functions of piRNAs in human diseases

X Wu, Y Pan, Y Fang, J Zhang, M Xie, F Yang… - … Therapy-Nucleic Acids, 2020 - cell.com
Piwi-interacting RNAs (piRNAs) are a novel type of small noncoding RNAs, which are 26–30
nt in length and bind to Piwi proteins. These short RNAs were originally discovered in …

[HTML][HTML] Unique somatic and malignant expression patterns implicate PIWI-interacting RNAs in cancer-type specific biology

VD Martinez, EA Vucic, KL Thu, R Hubaux… - Scientific reports, 2015 - nature.com
Abstract Human PIWI-interacting RNAs (piRNAs) are known to be expressed in germline
cells, functionally silencing LINEs and SINEs. Their expression patterns in somatic tissues …

Delivering the promise of gene therapy with nanomedicines in treating central nervous system diseases

M Luo, LKC Lee, B Peng, CHJ Choi… - Advanced …, 2022 - Wiley Online Library
Abstract Central Nervous System (CNS) diseases, such as Alzheimer's diseases (AD),
Parkinson's Diseases (PD), brain tumors, Huntington's disease (HD), and stroke, still remain …

[HTML][HTML] The biogenesis and biological function of PIWI-interacting RNA in cancer

S Chen, S Ben, J Xin, S Li, R Zheng, H Wang… - Journal of hematology & …, 2021 - Springer
Small non-coding RNAs (ncRNAs) are vital regulators of biological activities, and aberrant
levels of small ncRNAs are commonly found in precancerous lesions and cancer. PIWI …