Distinct from the traditional diagnostic/prognostic biomarker (adopted as the indicator of
disease state/process), the therapeutic biomarker (ThMAR) has emerged to be very crucial …

Cell counting in fluorescence microscopy is an essential task in biomedical research for
analyzing cellular dynamics and studying disease progression. Traditional methods for cell …

Cancer comes in second place on the list of causes of death worldwide. In 2018, the 5-year
prevalence of breast cancer (BC), prostate cancer (PC), and colorectal cancer (CRC) were …

Introduction Prostate cancer (PC) is the most common malignancy and accounts for a
significant proportion of cancer deaths among men. Although initial therapy success can …

Single-cell RNA sequencing (scRNA-seq) greatly advanced the understanding of
intratumoral heterogeneity by identifying distinct cancer cell subpopulations. However …

A thorough understanding of cell-line drug response mechanisms is crucial for drug
development, repurposing, and resistance reversal. While targeted anticancer therapies …

Single-cell RNA sequencing greatly advanced our understanding of intratumoral
heterogeneity through identifying tumor subpopulations with distinct biologies. However …

Simple Summary The major impact from this work is two-fold, first in providing a list of
reproducible candidate drugs nominated against multiple glioblastoma (GBM) datasets, and …

Cancer is a broad category of disease that can start in virtually any organ or tissue of the
body when aberrant cells assault surrounding organs and proliferate uncontrollably …