The circadian rhythm is a nearly 24‐h oscillation found in various physiological processes in
the human brain and body that is regulated by environmental and genetic factors. It is …

Sleep plays an essential role in all studied animals with a nervous system. However, sleep
deprivation leads to various pathological changes and neurobehavioral problems …

The brain is a complex organ, fundamentally changing across the day to perform basic
functions like sleep, thought, and regulating whole-body physiology. This requires a …

Mammalian physiology and cellular function are subject to significant oscillations over the
course of every 24-hour day. It is likely that these daily rhythms will affect function as well as …

Circadian rhythm dysfunction is a hallmark of Parkinson disease (PD), and diminished
expression of the core clock gene Bmal1 has been described in patients with PD. BMAL1 is …

The metabolic signals that regulate sleep and the metabolic functions that occur during
sleep are active areas of research. Prior studies have focused on sugars and nucleotides …

Benzotriazoles (BTRs) are a class of benzoheterocyclic chemicals that are frequently used
as metal-corrosive inhibitors, both in industry and daily use. However, the exposure effect …

Background Circadian rhythm disruption (CRD) is thought to increase the risk of
inflammatory bowel disease. The deletion of Bmal1, a core transcription factor, leads to a …

Sleep and circadian rhythms are observed broadly throughout animal phyla and influence
neural plasticity and cognitive function. However, the few phylogenetically conserved …

Background The treatment of metabolic system, cardiovascular system, and nervous system
diseases remains to be explored. In the internal environment of organisms, the metabolism …