Addictions are heritable and unfold dynamically across the lifespan. One prominent
neurobiological theory proposes that substance-induced changes in neural circuitry promote …

Objective Understanding how recreational cannabis legalization may impact cannabis use
disorder (CUD) among adolescents and young adults is key to developing an appropriate …

Objective: The causes of substance use disorders (SUDs) are largely unknown and the
effectiveness of their treatments is limited. One crucial impediment to research and treatment …

The prevalence of obesity doubled since the 1980s, resulting in exponentially higher
incidence rates of diet-related diseases [1, 2]. These drastic changes cannot be attributed to …

Cannabis use disorder (CUD) is widespread, and there is no pharmacotherapy to facilitate
its treatment. AEF0117, the first of a new pharmacological class, is a signaling-specific …

Substance use disorders (SUDs) are highly prevalent and exact a large toll on individuals'
health, well‐being, and social functioning. Long‐lasting changes in brain networks involved …

Tobacco use disorder (TUD) is the most prevalent substance use disorder in the world.
Genetic factors influence smoking behaviours and although strides have been made using …

Smoking of cigarettes among young adolescents is a pressing public health issue. However,
the neural mechanisms underlying smoking initiation and sustenance during adolescence …

Importance Alcohol misuse in adolescence is a leading cause of disability and mortality in
youth and is associated with higher risk for alcohol use disorder. Brain mechanisms …

The persistent difficulty in conceptualizing the relationship between addictive and other
mental disorders stands out among the many challenges faced by the field of Psychiatry …