Neurodegenerative diseases (NDs) such as Alzheimer disease (AD), Parkinson disease
(PD), and Huntington disease (HD) represent a major socio-economic challenge in view of …

The discovery and application of antibiotics in the common clinical practice has undeniably
been one of the major medical advances in our times. Their use meant a drastic drop in …

Mitochondrial health is based on a delicate balance of specific mitochondrial functions (eg
metabolism, signaling, dynamics) that are impaired in neurodegenerative diseases …

Parkinson's disease (PD) and dementia with Lewy bodies (DLB) are neurodegenerative
disorders characterized by the misfolding and aggregation of alpha-synuclein (aSyn) …

Neurodegeneration is a condition of the central nervous system (CNS) characterized by loss
of neural structures and function. The most common neurodegenerative disorders (NDDs) …

Neurodegenerative diseases (NDs) are characterized by uncontrolled loss of neuronal cells
leading to a progressive deterioration of brain functions. The transition rate of numerous …

Huntington's disease (HD) is one of main neurodegenerative diseases, characterized by
striatal atrophy, involuntary movements, and motor incoordination. Ginsenoside Rg1 (Rg1) …

Mechanisms of tissue damage in Huntington's disease involve excitotoxicity, mitochondrial
damage, and neuroinflammation, including microglia activation. In the present study, we …

Neurodegenerative polyglutamine (polyQ) disorders are caused by trinucleotide repeat
expansions within the coding region of disease-causing genes. PolyQ-expanded proteins …

Abstract After Alzheimer's disease, Parkinson's disease is the most frequent
neurodegenerative disorder. Although numerous treatments have been developed to control …