Chemical strategies to boost cancer vaccines

WH Li, YM Li - Chemical reviews, 2020 - ACS Publications
Personalized cancer vaccines (PCVs) are reinvigorating vaccine strategies in cancer
immunotherapy. In contrast to adoptive T-cell therapy and checkpoint blockade, the PCV …

[HTML][HTML] The human papillomavirus (HPV)-related cancer biology: An overview

RP Araldi, TA Sant'Ana, DG Módolo, TC de Melo… - Biomedicine & …, 2018 - Elsevier
Despite the novel diagnostic methods and therapies implemented in oncology, the number
of patients that succumb by the cancer remains high globally. Currently studies point out that …

Viral oncology: molecular biology and pathogenesis

UN Mui, CT Haley, SK Tyring - Journal of clinical medicine, 2017 - mdpi.com
Oncoviruses are implicated in approximately 12% of all human cancers. A large number of
the world's population harbors at least one of these oncoviruses, but only a small proportion …

Durability of single-dose HPV vaccination in young Kenyan women: randomized controlled trial 3-year results

RV Barnabas, ER Brown, MA Onono, EA Bukusi… - Nature Medicine, 2023 - nature.com
Cervical cancer burden is high where prophylactic vaccination and screening coverage are
low. We demonstrated in a multicenter randomized, double-blind, controlled trial that single …

Recent advances in the production of recombinant subunit vaccines in Pichia pastoris

M Wang, S Jiang, Y Wang - Bioengineered, 2016 - Taylor & Francis
Recombinant protein subunit vaccines are formulated using defined protein antigens that
can be produced in heterologous expression systems. The methylotrophic yeast Pichia …

Molecular tests potentially improving HPV screening and genotyping for cervical cancer prevention

A Gradíssimo, RD Burk - Expert Review of Molecular Diagnostics, 2017 - Taylor & Francis
ABSTRACT Introduction: Human papillomavirus (HPV)-related cancers can be averted by
type-specific vaccination (primary prevention) and/or through detection and ablation of …

Human papillomavirus and its vaccination: Knowledge and attitudes among female university students in Saudi Arabia

T Altamimi - Journal of Family Medicine and Primary Care, 2020 - journals.lww.com
Aim: This study aimed to assess the level of knowledge of cervical cancer and its risk factors,
as well as HPV vaccine acceptance among female students in Saudi Arabia enrolled in …

miR-106a regulates cell proliferation and autophagy by targeting LKB1 in HPV-16–associated cervical cancer

X Cui, X Wang, X Zhou, J Jia, H Chen, W Zhao - Molecular Cancer Research, 2020 - AACR
Abstract miR-106a is aberrantly regulated in various tumors and plays an important role in
carcinogenesis. However, the biological role and molecular mechanism by which miR-106a …

Cervical cancer: Screening, management, and prevention

BA Wuerthner, M Avila-Wallace - The Nurse Practitioner, 2016 - journals.lww.com
Cervical cancer incidence in the United States is estimated to affect 12,900 women in 2016,
with 4,100 deaths. Screening for this cancer with Pap test and adjunct human papillomavirus …

Combination therapy using human papillomavirus L1/E6/E7 genes and archaeosome: A nanovaccine confer immuneadjuvanting effects to fight cervical cancer

H Karimi, H Soleimanjahi, A Abdoli, RS Banijamali - Scientific Reports, 2020 - nature.com
Cancer is a leading cause of death worldwide. Cervical cancer caused by human
papillomavirus (HPV) is a major health problem in women. DNA vaccines are a perfect …