Bovine xenograft materials, followed by synthetic biomaterials, which unfortunately still lack
documented predictability and clinical performance, dominate the market for the cranio …

Biomedical implants have been widely used in various orthopedic treatments, including total
hip arthroplasty, joint arthrodesis, fracture fixation, non-union, dental repair, etc. The modern …

Adipose-derived stem cells (ADSCs) play critical roles in controlling obesity-associated
inflammation and metabolic disorders. Exosomes from ADSCs exert protective effects in …

Annually, millions of patients suffer from irreversible injury owing to the loss or failure of an
organ or tissue caused by accident, aging, or disease. The combination of injectable …

Administration of exosomes is considered an attractive cell-free approach to skeletal repair
and pathological disease treatment. However, poor yield for the production technique and …

Cell-laden hydrogels are widely used in tissue engineering and regenerative medicine.
However, many of these hydrogels are not optimized for use in the oral environment, where …

The regeneration of bone fractures, resulting from trauma, osteoporosis or tumors, is a major
problem in our super-aging society. Bone regeneration is one of the main topics of concern …

Healing and regeneration of bone injuries, particularly those that are associated with large
bone defects, are a complicated process. There is growing interest in the application of …

In modern medicine, bone and dental loss and defects are common and widespread
morbidities, for which regenerative therapy has shown great promise. Mesenchymal stem …

Bone tissue undergoes constant turnover supported by stem cells. Recent studies showed
that perivascular mesenchymal stem cells (MSCs) contribute to the turnover of long bones …