Malignant progression is greatly affected by dynamic cross-talk between stromal and cancer
cells. Exosomes are secreted nanovesicles that have key roles in cell–cell communication …

Citrate plays a central role in cancer cells' metabolism and regulation. Derived from
mitochondrial synthesis and/or carboxylation of α-ketoglutarate, it is cleaved by ATP-citrate …

Hepatocellular carcinoma is one of the most prevalent and lethal cancers with limited
therapeutic options. Pathogenesis of this disease involves tumor hypoxia and the activation …

Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive malignancy characterized
by its sudden manifestation, rapid progression, poor prognosis, and limited therapeutic …

Background/Aims: To investigate the biological roles and underlying molecular mechanisms
of long non-coding RNA (lncRNA) PVT1 in Hepatocellular carcinoma (HCC). Methods: qRT …

Hepatocellular carcinoma (HCC) is the malignancy derived from normal hepatocytes with
increasing incidence and extremely poor prognosis worldwide. The only approved first‐line …

Aptamers are small synthetic oligonucleotides that bind to target proteins with high
specificity and affinity. AS1411 is an aptamer that binds to nucleolin, which is overexpressed …

Liver cancer is the third greatest cause of cancer-related mortality, which of the major
pathological type is hepatocellular carcinoma (HCC) accounting for more than 90%. HCC is …

Growing interest is recently being focused on the role played by the platelets in favoring
hepatocellular cancer (HCC) growth and dissemination. The present review reports in detail …

The novelty of an effective therapeutic targeting for hepatocellular carcinoma (HCC) is
based on improved understanding of each component of tumor microenvironment (TME) …