[HTML][HTML] Designing enhanced spray dried particles for inhalation: A review of the impact of excipients and processing parameters on particle properties
Spray drying is a constructive single-step manufacturing technique used to produce dry
powder. Spray drying plays a remarkable role in producing inhalable powder formulations …
powder. Spray drying plays a remarkable role in producing inhalable powder formulations …
Virus-like particles as an instrument of vaccine production
BV Syomin, YV Ilyin - Molecular biology, 2019 - Springer
The paper discusses the techniques which are currently implemented for vaccine production
based on virus-like particles (VLPs). The factors which determine the characteristics of VLP …
based on virus-like particles (VLPs). The factors which determine the characteristics of VLP …
Exploiting gelatin nanocarriers in the pulmonary delivery of methotrexate for lung cancer therapy
Gelatin has many merits that encourage its use in the pulmonary delivery of anticancer
drugs. It is a biodegradable denatured protein which possesses several functional groups …
drugs. It is a biodegradable denatured protein which possesses several functional groups …
The future of dry powder inhaled therapy: Promising or discouraging for systemic disorders?
Y Ye, Y Ma, J Zhu - International journal of pharmaceutics, 2022 - Elsevier
Dry powder inhalation therapy has been shown to be an effective method for treating
respiratory diseases like asthma, Chronic Obstructive Pulmonary Diseases and Cystic …
respiratory diseases like asthma, Chronic Obstructive Pulmonary Diseases and Cystic …
Inhalable nanoparticle-based dry powder formulations for respiratory diseases: challenges and strategies for translational research
The emergence of novel respiratory infections (eg, COVID-19) and expeditious development
of nanoparticle-based COVID-19 vaccines have recently reignited considerable interest in …
of nanoparticle-based COVID-19 vaccines have recently reignited considerable interest in …
Polyglycerol hyperbranched polyesters: Synthesis, properties and pharmaceutical and biomedical applications
A Zamboulis, EA Nakiou, E Christodoulou… - International journal of …, 2019 - mdpi.com
In a century when environmental pollution is a major issue, polymers issued from bio-based
monomers have gained important interest, as they are expected to be environment-friendly …
monomers have gained important interest, as they are expected to be environment-friendly …
Pulmonary delivery of Nanocomposite Microparticles (NCMPs) incorporating miR-146a for treatment of COPD
The treatment and management of COPD by inhalation to the lungs has emerged as an
attractive alternative route to oral dosing due to higher concentrations of the drug being …
attractive alternative route to oral dosing due to higher concentrations of the drug being …
Polymeric nanoparticles for the delivery of miRNA to treat Chronic Obstructive Pulmonary Disease (COPD)
RNA interference (RNAi) based therapeutics are considered an endogenous mechanism for
modulating gene expression. In addition, microRNAs (miRNAs) may be tractable targets for …
modulating gene expression. In addition, microRNAs (miRNAs) may be tractable targets for …
Albumin nanocarriers for pulmonary drug delivery: An attractive approach
M Joshi, M Nagarsenkar, B Prabhakar - Journal of Drug Delivery Science …, 2020 - Elsevier
Biodegradable polymers are drawing a great deal of attention in the field of nanotechnology.
Albumin, abundantly present in human body, is a biocompatible and biodegradable polymer …
Albumin, abundantly present in human body, is a biocompatible and biodegradable polymer …
Repurposing bedaquiline for effective non-small cell lung cancer (NSCLC) therapy as inhalable cyclodextrin-based molecular inclusion complexes
There is growing evidence that repurposed drugs demonstrate excellent efficacy against
many cancers, while facilitating accelerated drug development process. In this study …
many cancers, while facilitating accelerated drug development process. In this study …