[HTML][HTML] Designing enhanced spray dried particles for inhalation: A review of the impact of excipients and processing parameters on particle properties

N Alhajj, NJ O'Reilly, H Cathcart - Powder Technology, 2021 - Elsevier
Spray drying is a constructive single-step manufacturing technique used to produce dry
powder. Spray drying plays a remarkable role in producing inhalable powder formulations …

Virus-like particles as an instrument of vaccine production

BV Syomin, YV Ilyin - Molecular biology, 2019 - Springer
The paper discusses the techniques which are currently implemented for vaccine production
based on virus-like particles (VLPs). The factors which determine the characteristics of VLP …

Exploiting gelatin nanocarriers in the pulmonary delivery of methotrexate for lung cancer therapy

H Abdelrady, RM Hathout, R Osman, I Saleem… - European journal of …, 2019 - Elsevier
Gelatin has many merits that encourage its use in the pulmonary delivery of anticancer
drugs. It is a biodegradable denatured protein which possesses several functional groups …

The future of dry powder inhaled therapy: Promising or discouraging for systemic disorders?

Y Ye, Y Ma, J Zhu - International journal of pharmaceutics, 2022 - Elsevier
Dry powder inhalation therapy has been shown to be an effective method for treating
respiratory diseases like asthma, Chronic Obstructive Pulmonary Diseases and Cystic …

Inhalable nanoparticle-based dry powder formulations for respiratory diseases: challenges and strategies for translational research

HW Chan, S Chow, X Zhang, Y Zhao, HHY Tong… - AAPS …, 2023 - Springer
The emergence of novel respiratory infections (eg, COVID-19) and expeditious development
of nanoparticle-based COVID-19 vaccines have recently reignited considerable interest in …

Polyglycerol hyperbranched polyesters: Synthesis, properties and pharmaceutical and biomedical applications

A Zamboulis, EA Nakiou, E Christodoulou… - International journal of …, 2019 - mdpi.com
In a century when environmental pollution is a major issue, polymers issued from bio-based
monomers have gained important interest, as they are expected to be environment-friendly …

Pulmonary delivery of Nanocomposite Microparticles (NCMPs) incorporating miR-146a for treatment of COPD

A Mohamed, AY Pekoz, K Ross, GA Hutcheon… - International Journal of …, 2019 - Elsevier
The treatment and management of COPD by inhalation to the lungs has emerged as an
attractive alternative route to oral dosing due to higher concentrations of the drug being …

Polymeric nanoparticles for the delivery of miRNA to treat Chronic Obstructive Pulmonary Disease (COPD)

A Mohamed, NK Kunda, K Ross, GA Hutcheon… - European Journal of …, 2019 - Elsevier
RNA interference (RNAi) based therapeutics are considered an endogenous mechanism for
modulating gene expression. In addition, microRNAs (miRNAs) may be tractable targets for …

Albumin nanocarriers for pulmonary drug delivery: An attractive approach

M Joshi, M Nagarsenkar, B Prabhakar - Journal of Drug Delivery Science …, 2020 - Elsevier
Biodegradable polymers are drawing a great deal of attention in the field of nanotechnology.
Albumin, abundantly present in human body, is a biocompatible and biodegradable polymer …

Repurposing bedaquiline for effective non-small cell lung cancer (NSCLC) therapy as inhalable cyclodextrin-based molecular inclusion complexes

V Parvathaneni, RS Elbatanony, M Goyal… - International journal of …, 2021 - mdpi.com
There is growing evidence that repurposed drugs demonstrate excellent efficacy against
many cancers, while facilitating accelerated drug development process. In this study …