Evolution of the human pathogenic lifestyle in fungi
A Rokas - Nature Microbiology, 2022 - nature.com
Fungal pathogens cause more than a billion human infections every year, resulting in more
than 1.6 million deaths annually. Understanding the natural history and evolutionary ecology …
than 1.6 million deaths annually. Understanding the natural history and evolutionary ecology …
An overlooked and underrated endemic mycosis—Talaromycosis and the pathogenic fungus Talaromyces marneffei
F Wang, RH Han, S Chen - Clinical Microbiology Reviews, 2023 - Am Soc Microbiol
Talaromycosis is an invasive mycosis endemic in tropical and subtropical Asia and is
caused by the pathogenic fungus Talaromyces marneffei. Approximately 17,300 cases of T …
caused by the pathogenic fungus Talaromyces marneffei. Approximately 17,300 cases of T …
Population genomics confirms acquisition of drug-resistant Aspergillus fumigatus infection by humans from the environment
Infections caused by the fungal pathogen Aspergillus fumigatus are increasingly resistant to
first-line azole antifungal drugs. However, despite its clinical importance, little is known …
first-line azole antifungal drugs. However, despite its clinical importance, little is known …
The pan-genome of Aspergillus fumigatus provides a high-resolution view of its population structure revealing high levels of lineage-specific diversity driven by …
Aspergillus fumigatus is a deadly agent of human fungal disease where virulence
heterogeneity is thought to be at least partially structured by genetic variation between …
heterogeneity is thought to be at least partially structured by genetic variation between …
Genome-scale metabolic modeling of Aspergillus fumigatus strains reveals growth dependencies on the lung microbiome
Aspergillus fumigatus, an opportunistic human pathogen, frequently infects the lungs of
people with cystic fibrosis and is one of the most common causes of infectious-disease …
people with cystic fibrosis and is one of the most common causes of infectious-disease …
[PDF][PDF] Microbiota manipulation through the secretion of effector proteins is fundamental to the wealth of lifestyles in the fungal kingdom
NC Snelders, H Rovenich… - FEMS Microbiology …, 2022 - academic.oup.com
Fungi are well-known decomposers of organic matter that thrive in virtually any environment
on Earth where they encounter wealths of other microbes. Some fungi evolved symbiotic …
on Earth where they encounter wealths of other microbes. Some fungi evolved symbiotic …
The human fungal pathogen Aspergillus fumigatus can produce the highest known number of meiotic crossovers
Sexual reproduction involving meiosis is essential in most eukaryotes. This produces
offspring with novel genotypes, both by segregation of parental chromosomes as well as …
offspring with novel genotypes, both by segregation of parental chromosomes as well as …
A heterologous expression platform in Aspergillus nidulans for the elucidation of cryptic secondary metabolism biosynthetic gene clusters: discovery of the Aspergillus …
Aspergillus fumigatus is a serious human pathogen causing life-threatening Aspergillosis in
immunocompromised patients. Secondary metabolites (SMs) play an important role in …
immunocompromised patients. Secondary metabolites (SMs) play an important role in …
Combined pangenomics and transcriptomics reveals core and redundant virulence processes in a rapidly evolving fungal plant pathogen
H Chen, R King, D Smith, C Bayon, T Ashfield… - BMC biology, 2023 - Springer
Background Studying genomic variation in rapidly evolving pathogens potentially enables
identification of genes supporting their “core biology”, being present, functional and …
identification of genes supporting their “core biology”, being present, functional and …
Recent advances and future directions in the understanding of mucormycosis
V Garre - Frontiers in Cellular and Infection Microbiology, 2022 - frontiersin.org
Mucormycosis is an emerging infection caused by fungi of the order Mucorales that has
recently gained public relevance due to the high incidence among COVID-19 patients in …
recently gained public relevance due to the high incidence among COVID-19 patients in …