The Infectious Diseases Society of America guidelines on the diagnosis of COVID-19: antigen testing

MK Hayden, KE Hanson, JA Englund… - Clinical Infectious …, 2023 - academic.oup.com
Immunoassays designed to detect SARS-CoV-2 protein antigens (Ag) are commonly used to
diagnose COVID-19. The most widely used tests are lateral flow assays that generate results …

[HTML][HTML] The role of SARS-CoV-2 N protein in diagnosis and vaccination in the context of emerging variants: Present status and prospects

W Song, Z Fang, F Ma, J Li, Z Huang, Y Zhang… - Frontiers in …, 2023 - frontiersin.org
Despite many countries rapidly revising their strategies to prevent contagions, the number of
people infected with Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) …

[HTML][HTML] Emerging trends in point-of-care biosensing strategies for molecular architectures and antibodies of SARS-CoV-2

G Karuppaiah, A Vashist, M Nair… - … and Bioelectronics: X, 2023 - Elsevier
COVID-19, a highly contagious viral infection caused by the occurrence of severe acute
respiratory syndrome coronavirus (SARS-CoV-2), has turned out to be a viral pandemic then …

Sensitivity of rapid antigen tests against SARS-CoV-2 Omicron and Delta variants

A Rao, A Westbrook, L Bassit, R Parsons… - Journal of Clinical …, 2023 - Am Soc Microbiol
Rapid antigen tests (RATs) have become an invaluable tool for combating the COVID-19
pandemic. However, concerns have been raised regarding the ability of existing RATs to …

[HTML][HTML] Deep mutational scanning of proteins in mammalian cells

S Maes, N Deploey, F Peelman, S Eyckerman - Cell Reports Methods, 2023 - cell.com
Protein mutagenesis is essential for unveiling the molecular mechanisms underlying protein
function in health, disease, and evolution. In the past decade, deep mutational scanning …

[HTML][HTML] Functional and antigenic characterization of SARS-CoV-2 spike fusion peptide by deep mutational scanning

R Lei, E Qing, A Odle, M Yuan… - Nature …, 2024 - nature.com
The fusion peptide of SARS-CoV-2 spike protein is functionally important for membrane
fusion during virus entry and is part of a broadly neutralizing epitope. However, sequence …

[HTML][HTML] Next-generation vaccines against COVID-19 variants: beyond the spike protein

SR Bonam, H Hu - Zoonoses (Burlington, Mass.), 2023 - ncbi.nlm.nih.gov
Vaccines are among the most effective medical countermeasures against infectious
diseases. The current Coronavirus disease 2019 (COVID-19) pandemic, caused by severe …

[HTML][HTML] Enhancing a SARS-CoV-2 nucleocapsid antigen test sensitivity with cost efficient strategy through a cotton intermembrane insertion

DRP Nicollete, R Benedetti, BA Valença… - Scientific Reports, 2023 - nature.com
Lateral flow antigen tests have been widely used in the Covid-19 pandemic, allowing faster
diagnostic test results and preventing further viral spread through isolation of infected …

[HTML][HTML] Efficient overexpression and purification of severe acute respiratory syndrome coronavirus 2 nucleocapsid proteins in Escherichia coli

EL Brudenell, MB Pohare, D Zafred, J Phipps… - Biochemical …, 2024 - portlandpress.com
The fundamental biology of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
nucleocapsid protein (Ncap), its use in diagnostic assays and its potential application as a …

Accelerated Development of a COVID-19 Lateral Flow Test in an Academic Setting: Lessons Learned

K Kourentzi, K Brosamer, B Vu… - Accounts of Chemical …, 2024 - ACS Publications
Conspectus The COVID-19 pandemic further demonstrated the need for usable, reliable,
and cost-effective point-of-care diagnostics that can be broadly deployed, ideally for self …