Clinical and epidemiological studies indicate that obesity affects the development and
phenotype of asthma by inducing inflammatory mechanisms in addition to eosinophilic …

Insulin and exercise stimulate glucose uptake into skeletal muscle via different pathways.
Both stimuli converge on the translocation of the glucose transporter GLUT4 from …

(1) Background: studies on the long-term dynamic changes in fat depot metabolism in
response to a high-fat diet (HFD) on hepatic lipid deposition and insulin resistance are …

Obesity is an established risk factor for many cancers and has recently been found to alter
the efficacy of T cell–based immunotherapies. Currently, however, the effects of obesity on …

The sharp increase in obesity prevalence worldwide is mainly attributable to changes in
physical activity and eating behavior but the metabolic and clinical impacts of these …

Diet-induced obesity (DIO) is associated with glucose intolerance, insulin resistance (IR),
and an increase in intramyocellular lipids (IMCL), which may lead to disturbances in glucose …

Abstract Non-alcoholic steatohepatitis (NASH), characterized as the joint presence of
steatosis, hepatocellular ballooning and lobular inflammation, and liver fibrosis are strong …

Obese women have higher risk of bearing breast tumors that are highly aggressive and
resistant to therapies. Tumor-promoting effects of obesity occur locally via adipose …

Exposure to particulate matter (PM) from traffic vehicles is hazardous to the vascular system,
leading to clinical manifestations and mortality due to ischemic heart disease. By analogy …

Background The alarming rise of obesity and its associated comorbidities represents a
medical burden and a major global health and economic issue. Understanding etiological …