In recent years, the demand for novel antifungal therapies has increased several-folds due
to its potential to treat severe biofilm-associated infections. Biofilms are made by the sessile …

Candida albicans remains the main etiological agent of candidiasis, as this otherwise
normal commensal of humans is capable of causing active infection in immune-and …

Background Candida albicans is the most common pathogenic fungus isolated in
bloodstream infections in hospitalized patients, and candidiasis represents the fourth most …

When microorganisms live together in high numbers, they need to communicate with each
other. To achieve cell–cell communication, microorganisms secrete molecules called …

Candida albicans is a normal member of the human microbiota that asymptomatically
colonizes healthy individuals, however it is also an opportunistic pathogen that can cause …

The high incidence and mortality of invasive fungal infections and serious drug resistance
have become a global public health issue. The ability of fungal cells to form biofilms is an …

Candida albicans has remained the main etiological agent of candidiasis, challenges
clinicians with high mortality and morbidity. The emergence of resistance to antifungal drugs …

Candida albicans biofilms have a significant medical impact due to their rapid growth on
implanted medical devices, their resistance to antifungal drugs, and their ability to seed …

Candida albicans biofilms are a complex multilayer community of cells that are resistant to
almost all classes of antifungal drugs. The bottommost layers of biofilms experience nutrient …

The incidence of fungal infections has been increasing in the last decades, while the
number of available antifungal classes remains the same. The natural and acquired …