Biology of natural killer cells

G Trinchieri - Advances in immunology, 1989 - Elsevier
Publisher Summary Studies of cytotoxicity by human lymphocytes revealed not only that
both allogeneic and syngeneic tumor cells were lysed in a non-MHC-restricted fashion, but …

Natural killer cytotoxicity in the diagnosis of immune dysfunction: criteria for a reproducible assay

TL Whiteside, J Bryant… - Journal of clinical …, 1990 - Wiley Online Library
Current evidence indicates that natural killer (NK) cells, which are large granular
lymphocytes that mediate non‐major histocompatibility complex (MHC)‐restricted …

Increased number of circulating Leu 11+(CD 16) large granular lymphocytes and decreased NK activity during human ageing.

A Facchini, E Mariani, AR Mariani, S Papa… - Clinical and …, 1987 - ncbi.nlm.nih.gov
The phenotype and functional activity of circulating T and natural killer (NK) cells was
investigated in a group of selected normal elderly donors in comparison with a group of …

The antiabortive effect of progesterone-induced blocking factor in mice is manifested by modulating NK activity

J Szekeres-Bartho, G Par, GY Dombay, YC Smart… - Cellular …, 1997 - Elsevier
Immunologic effects of progesterone are mediated by a protein named the progesterone-
induced blocking factor (PIBF), which inhibits NK activity and displays an antiabortive effect …

Characteristics of a monoclonal antibody (WT-31) that recognizes a common epitope on the human T cell receptor for antigen.

H Spits, J Borst, W Tax, PJ Capel… - … (Baltimore, Md.: 1950 …, 1985 - journals.aai.org
We describe a monoclonal antibody, WT-31, that reacted with all human T lymphocytes.
Electrophoretic analysis of the material reacting with WT-31 revealed that it precipitated …

Mechanisms of diminished natural killer cell activity in pregnant women and neonates.

JE Baley, BZ Schacter - Journal of immunology (Baltimore, Md …, 1985 - journals.aai.org
Because alterations in natural killer (NK) activity in the perinatal period may be important in
the maintenance of a healthy pregnancy, we examined the mechanisms by which these …

The role of γ/δ T cell receptor positive cells in pregnancy

B Polgar, A Barakonyi, I Xynos… - American Journal of …, 1999 - Wiley Online Library
PROBLEM: Due to the lack of classical HLA antigens on the trophoblast, fetal antigens are
possibly presented in a non major histocompatibility complex (MHC) restricted way …

LFA-1 and other accessory molecules functioning in adhesions of T and B lymphocytes

E Martz - Human immunology, 1987 - Elsevier
Adhesions of lymphocytes, among themselves or with other cell types, are necessary for
most steps in immune responses including both induction and effector phases. Among …

Decrease in CD3-negative-CD8dim+ and Vδ2/Vγ9 TcR+ peripheral blood lymphocyte counts, low perforin expression and the impairment of natural killer cell activity …

G Pár, D Rukavina, ER Podack, M Horányi… - Journal of …, 2002 - Elsevier
Background/Aims: As chronic hepatitis C virus (HCV) infection is associated with impaired
natural killer (NK) cell cytotoxicity, we examined the phenotypes and perforin expression of …

Marijuana components suppress induction and cytolytic function of murine cytotoxic T cells in vitro and in vivo

TW Klein, Y Kawakami, C Newton… - Journal of Toxicology …, 1991 - Taylor & Francis
Killer lymphocytes play a major role in host defense against tumors and infectious diseases.
Previously, we reported that delta‐9‐tetrahydrocannabinol (THC) and II‐hydroxy‐delta‐9 …