Macrophages exist in various tissues, several body cavities, and around mucosal surfaces
and are a vital part of the innate immune system for host defense against many pathogens …

Tumour progression is modulated by the local microenvironment. This environment is
populated by many immune cells, of which macrophages are among the most abundant …

The heterogeneity of tissue macrophages, in health and in disease, has become
increasingly transparent over the last decade. But with the plethora of data comes a natural …

Eukaryotic cells have developed complex systems to regulate the production and response
to reactive oxygen species (ROS). Different ROS control diverse aspects of cell behaviour …

Non-alcoholic fatty liver disease (NAFLD) is the most prevalent chronic liver disease and is
emerging as the leading cause of cirrhosis, liver transplantation and hepatocellular …

Single-cell and spatial transcriptomic technologies have revealed an underappreciated
heterogeneity of liver macrophages. This has led us to rethink the involvement of …

Long recognized as an evolutionarily ancient cell type involved in tissue homeostasis and
immune defense against pathogens, macrophages are being re-discovered as regulators of …

Innate and adaptive immunity represent a harmonic counterbalanced system involved in the
induction, progression, and possibly resolution of the inflammatory reaction that characterize …

Myeloid-derived suppressor cells (MDSCs) are a heterogenic population of immature
myeloid cells with immunosuppressive effects, which undergo massive expansion during …

Molecular imaging via afterglow luminescence minimizes tissue autofluorescence and
increases the signal-to-noise ratio. However, the induction of afterglow requires the prior …