Airborne pollutants and the immune system
JF Albright, RA Goldstein - Otolaryngology--Head and Neck …, 1996 - journals.sagepub.com
The effects of airborne pollutants on the immune system have been most widely studied in
the respiratory tract. Entry may occur as a volatile gas (ozone, benzene), as liquid droplets …
the respiratory tract. Entry may occur as a volatile gas (ozone, benzene), as liquid droplets …
Antibodies and their fragments as anti-cancer agents
O Schaedel, Y Reiter - Current pharmaceutical design, 2006 - ingentaconnect.com
The recent developments in the field of recombinant DNA, protein engineering and cancer
biology, have let us gain insight into many cancer-related mechanisms. Moreover, novel …
biology, have let us gain insight into many cancer-related mechanisms. Moreover, novel …
Shaping the repertoire of cytotoxic T-lymphocyte responses: explanation for the immunodominance effect whereby cytotoxic T lymphocytes specific for …
S Pion, GJ Christianson, P Fontaine… - Blood, The Journal …, 1999 - ashpublications.org
The immunodominance effect, whereby the presence of immunodominant epitopes prevents
recognition of nondominant determinants presented on the same antigen-presenting cell …
recognition of nondominant determinants presented on the same antigen-presenting cell …
On the mechanisms of immunodominance in cytotoxic T lymphocyte responses to minor histocompatibility antigens
S Pion, P Fontaine, M Desaulniers… - European journal of …, 1997 - Wiley Online Library
Although there are numerous minor histocompatibility antigens (MiHA), T cell responses
leading to graft‐versus‐host (GVH) and graft‐versus‐tumor effects involve only a small …
leading to graft‐versus‐host (GVH) and graft‐versus‐tumor effects involve only a small …
Human ex vivo carcinoma cells produce transforming growth factor β and thereby can inhibit lymphocyte functions in vitro
F Vánky, N Nagy, C Hising, K Sjövall… - Cancer Immunology …, 1997 - Springer
We tested 20 human carcinoma samples for the production of transforming growth factor β
(TGFβ) in vitro. Tumour cell suspensions without obvious contamination with non-malignant …
(TGFβ) in vitro. Tumour cell suspensions without obvious contamination with non-malignant …
Immunodominant minor histocompatibility antigens expressed by mouse leukemic cells can serve as effective targets for T cell immunotherapy.
S Pion, P Fontaine, C Baron, M Gyger… - The Journal of …, 1995 - Am Soc Clin Investig
Numerous minor histocompatibility antigens (MiHAs) show tissue-specific expression and
can induce vigorous T cell responses. They therefore represent attractive targets for …
can induce vigorous T cell responses. They therefore represent attractive targets for …
Immunogenicity and immunosensitivity of ex vivo human carcinomas: interferon γ and tumour necrosis factor α treatment of tumour cells potentiates their interaction …
F Vánky, C Hising, K Sjöwall, B Larsson… - Cancer Immunology …, 1995 - Springer
Human carcinoma cells vary appreciably in the expression of MHC class I, class II, ICAM-1
(CD54) and B7 (CD80) molecules. Short-term in vitro exposure of ex vivo carcinoma cells to …
(CD54) and B7 (CD80) molecules. Short-term in vitro exposure of ex vivo carcinoma cells to …
次要组织相容性抗原在GVHD/GVL 中的作用及研究进展
何英， 吴松泽 - 华西医学, 2004 - cqvip.com
次要组织相容性抗原(miHAs) 是一组能被MHC-Ⅰ 或MHC-Ⅱ 分子连接和递呈的自身多肽(self-
peptide)[1]. miHAs 的编码基因分散在整个基因组中, 它们作为多态性的基因产物 …
peptide)[1]. miHAs 的编码基因分散在整个基因组中, 它们作为多态性的基因产物 …