[HTML][HTML] Combination of ablation and immunotherapy for hepatocellular carcinoma: where we are and where to go

K Wang, C Wang, H Jiang, Y Zhang, W Lin… - Frontiers in …, 2021 - frontiersin.org
Hepatocellular carcinoma (HCC) is the third leading cause of cancer-related deaths
worldwide and is increasing in incidence. Local ablative therapy plays a leading role in HCC …

General rules for the clinical and pathological study of primary liver cancer, nationwide follow-up survey and clinical practice guidelines: the outstanding achievements …

M Kudo, M Kitano, T Sakurai, N Nishida - Digestive diseases, 2015 - karger.com
This review outlines the significance of establishing general rules, a nationwide follow-up
survey, and clinical practice guidelines for liver cancer in Japan. The general rules are an …

Immuno-oncology in hepatocellular carcinoma: 2017 update

M Kudo - Oncology, 2017 - karger.com
Clinical trials are currently ongoing to evaluate the utility of antibodies against programmed
cell death 1 (PD-1), programmed cell death-ligand 1 (PD-L1), and cytotoxic T-lymphocyte …

A novel software platform for volumetric assessment of ablation completeness

M Solbiati, R Muglia, SN Goldberg… - International Journal …, 2019 - Taylor & Francis
Purpose: To retrospectively evaluate the accuracy of a novel software platform for assessing
completeness of percutaneous thermal ablations. Materials & methods: Ninety …

Exosome‐transferred long non‐coding RNA ASMTL‐AS1 contributes to malignant phenotypes in residual hepatocellular carcinoma after insufficient radiofrequency …

D Ma, X Gao, Z Liu, X Lu, H Ju, N Zhang - Cell Proliferation, 2020 - Wiley Online Library
Abstract Objectives Long non‐coding RNAs (lncRNAs) are emerging RNA regulators in
cancer progression, including in hepatocellular carcinoma (HCC). Recently, insufficient …

Targeting PI3Kγ/AKT Pathway Remodels LC3‐Associated Phagocytosis Induced Immunosuppression After Radiofrequency Ablation

X Liu, W Zhang, Y Xu, X Xu, Q Jiang, J Ruan… - Advanced …, 2022 - Wiley Online Library
Residual tumors after insufficient radiofrequency ablation (IRFA) shows accelerated
progression and anti‐PD‐1 resistance. It is also reported that macrophages infiltrating into …

ICAM‐1 activates platelets and promotes endothelial permeability through VE‐cadherin after insufficient radiofrequency ablation

J Kong, C Yao, S Dong, S Wu, Y Xu, K Li, L Ji… - Advanced …, 2021 - Wiley Online Library
Radiofrequency ablation (RFA) for hepatocellular carcinoma (HCC) often leads to
aggressive local recurrence and increased metastasis, and vascular integrity and platelets …

Insufficient radiofrequency ablation promotes proliferation of residual hepatocellular carcinoma via autophagy

Z Zhao, J Wu, X Liu, M Liang, X Zhou, S Ouyang, J Yao… - Cancer letters, 2018 - Elsevier
Radiofrequency ablation (RFA) is considered to be a potentially curative therapy for
hepatocellular carcinoma (HCC). However, insufficient RFA (IRFA) can promote rapid …

Transarterial chemoembolization in combination with a molecular targeted agent: lessons learned from negative trials (Post-TACE, BRISK-TA, SPACE, ORIENTAL …

M Kudo, T Arizumi - Oncology, 2017 - karger.com
The multikinase inhibitor sorafenib is the first oral molecular targeted agent with proven
prognostic benefit in unresectable advanced hepatocellular carcinoma (HCC). However, as …

Time to transcatheter arterial chemoembolization refractoriness in patients with hepatocellular carcinoma in Kinki criteria stages B1 and B2

T Arizumi, T Minami, H Chishina, M Kono, M Takita… - Digestive …, 2017 - karger.com
Background: Transarterial chemoembolization (TACE) is recommended for patients with
hepatocellular carcinoma (HCC) in Barcelona Clinic Liver Cancer (BCLC) stage B …