Amorphous solid dispersions enhance solubility and oral bioavailability of poorly water-
soluble drugs. The escalating number of drugs with poor aqueous solubility, poor …

As the advancements in the medical technology and healthcare develop through the years,
combinational therapy has evolved to be an important treatment modality in many disease …

Inspired by the natural phenomenon of phenolic–protein interactions, we translate this
“naturally evolved interaction” to a “phenolic acid derivative based albumin bound” …

Different from previously reported co-amorphous systems, a co-amorphous curcumin-
magnolol (CUR-MAG CM) system, as compared with its crystalline counterparts, exhibited …

Poor solubility of drugs and therapeutic candidates poses a significant challenge in drug
research and development. Biopharmaceutical class II drugs exhibit limited absorption …

It is well established that currently available inhaled drug formulations are associated with
extremely low lung deposition. Currently available technologies alleviate this low deposition …

In the previous study, the development of amorphous curcumin (CUR) aimed to enhance the
solubility/dissolution of CUR by disrupting its crystal lattice, but it unexpectedly showed a …

Overcoming the poor water solubility of small-molecule drugs is a major challenge in the
development of clinical pharmaceuticals. Amorphization of crystalline drugs is a highly …

Coamorphous drug delivery systems have shown great potential in improving the solubility
and bioavailability of poorly water-soluble drugs. However, the coamorphous formation …

The primary focus of the research is to study the role of cocrystal and amorphous solid
dispersion approaches for enhancing solubility and preserving the stability of a poorly …