Evaluation of antibiotic resistance mechanisms in gram-negative bacteria
A Gauba, KM Rahman - Antibiotics, 2023 - mdpi.com
Multidrug-resistant Gram-negative bacterial infections are exponentially increasing, posing
one of the most urgent global healthcare and economic threats. Due to the lack of new …
one of the most urgent global healthcare and economic threats. Due to the lack of new …
[HTML][HTML] AcrAB− TolC, a major efflux pump in Gram negative bacteria: toward understanding its operation mechanism
S Jang - BMB reports, 2023 - ncbi.nlm.nih.gov
Antibiotic resistance (AR) is a silent pandemic that kills millions worldwide. Although the
development of new therapeutic agents against antibiotic resistance is in urgent demand …
development of new therapeutic agents against antibiotic resistance is in urgent demand …
Inhibition of multidrug efflux pumps belonging to the major facilitator superfamily in bacterial pathogens
Bacterial pathogens resistant to multiple structurally distinct antimicrobial agents are
causative agents of infectious disease, and they thus constitute a serious concern for public …
causative agents of infectious disease, and they thus constitute a serious concern for public …
The balance between antibiotic resistance and fitness/virulence in Pseudomonas aeruginosa: an update on basic knowledge and fundamental research
E Jordana-Lluch, IM Barceló… - Frontiers in …, 2023 - frontiersin.org
The interplay between antibiotic resistance and bacterial fitness/virulence has attracted the
interest of researchers for decades because of its therapeutic implications, since it is …
interest of researchers for decades because of its therapeutic implications, since it is …
The Art of War with Pseudomonas aeruginosa: Targeting Mex Efflux Pumps Directly to Strategically Enhance Antipseudomonal Drug Efficacy
Pseudomonas aeruginosa (P. aeruginosa) poses a grave clinical challenge due to its
multidrug resistance (MDR) phenotype, leading to severe and life-threatening infections …
multidrug resistance (MDR) phenotype, leading to severe and life-threatening infections …
Mechanisms of Antibiotic and Biocide Resistance That Contribute to Pseudomonas aeruginosa Persistence in the Hospital Environment
C Verdial, I Serrano, L Tavares, S Gil, M Oliveira - Biomedicines, 2023 - mdpi.com
Pseudomonas aeruginosa is an opportunistic bacterial pathogen responsible for multiple
hospital-and community-acquired infections, both in human and veterinary medicine. P …
hospital-and community-acquired infections, both in human and veterinary medicine. P …
Nonlethal Molecular Nanomachines Potentiate Antibiotic Activity Against Gram-Negative Bacteria by Increasing Cell Permeability and Attenuating Efflux
Antibiotic resistance is a pressing public health threat. Despite rising resistance, antibiotic
development, especially for Gram-negative bacteria, has stagnated. As the traditional …
development, especially for Gram-negative bacteria, has stagnated. As the traditional …
Resistance in Pseudomonas aeruginosa: A Narrative Review of Antibiogram Interpretation and Emerging Treatments
Pseudomonas aeruginosa is a ubiquitous Gram-negative bacterium renowned for its
resilience and adaptability across diverse environments, including clinical settings, where it …
resilience and adaptability across diverse environments, including clinical settings, where it …
Emerging strategies to target virulence in Pseudomonas aeruginosa respiratory infections
TM Hibbert, M Whiteley, SA Renshaw… - Critical reviews in …, 2023 - Taylor & Francis
Pseudomonas aeruginosa is an opportunistic pathogen that is responsible for infections in
people living with chronic respiratory conditions, such as cystic fibrosis (CF) and non-CF …
people living with chronic respiratory conditions, such as cystic fibrosis (CF) and non-CF …
A molecular overview of the polymyxin-LPS interaction in the context of its mode of action and resistance development
I Padhy, SK Dwibedy, SS Mohapatra - Microbiological Research, 2024 - Elsevier
With the rising incidences of antimicrobial resistance (AMR) and the diminishing options of
novel antimicrobial agents, it is paramount to decipher the molecular mechanisms of action …
novel antimicrobial agents, it is paramount to decipher the molecular mechanisms of action …