We investigated in this study the pharmacological properties of AC-3933 (5-(3-
methoxyphenyl)-3-(5-methyl-1, 2, 4-oxadiazol-3-yl)-1, 6-naphthyridin-2 (1H)-one), a novel …

The neurodegenerative disorders are typically characterized by the gradual loss of neuronal
function and structure, also known as neurodegeneration. They are debilitating conditions …

Drug discovery is a continuous process where researchers are constantly trying to find new
and better drugs for the treatment of various conditions. Alzheimer's disease, a …

Adult neurogenesis, which is the development of new neurons in the brain, is a process that
is only rarely seen in adult mammals but is commonly seen in a variety of adult reptiles …

Psychopharmacology Bulletin is well into its sixth decade of publishing. During that time,
psychopharmacology has advanced as a medical discipline by maximizing research into the …

阿尔茨海默病患者脑内转化生长因子β 受体—TβRII 极度缺乏, 导致TGF-β1/SMADs
信号通路传导抑制, 从而加重了β 淀粉样蛋白的沉积和神经元的损伤. Dab2 …

The brain is the richest organ in terms of lipid content and diversity. Brain lipids play a wide
range of physiological functions at the cellular level including participating in membrane …

Recent work has contributed to understanding of the physiology of the brain endothelial
cells forming the blood–brain barrier (BBB), and their interaction with the associated cells of …