Peripheral nerve injury treatments and advances: one health perspective

B Lopes, P Sousa, R Alvites, M Branquinho… - International journal of …, 2022 - mdpi.com
Peripheral nerve injuries (PNI) can have several etiologies, such as trauma and iatrogenic
interventions, that can lead to the loss of structure and/or function impairment. These …

Bridging gaps in peripheral nerves: from current strategies to future perspectives in conduit design

E Stocco, S Barbon, A Emmi, C Tiengo… - International Journal of …, 2023 - mdpi.com
In peripheral nerve injuries (PNI) with substance loss, where tensionless end-to-end suture
is not achievable, the positioning of a graft is required. Available options include autografts …

[PDF][PDF] Adipo-glial signaling mediates metabolic adaptation in peripheral nerve regeneration

VK Sundaram, V Schütza, NH Schröter, A Backhaus… - Cell Metabolism, 2023 - cell.com
The peripheral nervous system harbors a remarkable potential to regenerate after acute
nerve trauma. Full functional recovery, however, is rare and critically depends on peripheral …

Design and fabrication of polymeric hydrogel carrier for nerve repair

X Ma, M Wang, Y Ran, Y Wu, J Wang, F Gao, Z Liu, J Xi… - Polymers, 2022 - mdpi.com
Nerve regeneration and repair still remain a huge challenge for both central nervous and
peripheral nervous system. Although some therapeutic substances, including …

Human platelet lysate stimulates neurotrophic properties of human adipose-derived stem cells better than Schwann cell-like cells

S Brambilla, M Guiotto, E Torretta, I Armenia… - Stem Cell Research & …, 2023 - Springer
Background Trauma-associated peripheral nerve injury is a widespread clinical problem
causing sensory and motor disabilities. Schwann cells (SCs) contribute to nerve …

The crosstalk between adipose-derived stem or stromal cells (ASC) and cancer cells and ASC-mediated effects on cancer formation and progression—ASCs: safety …

VGJ Guillaume, T Ruhl, AM Boos… - Stem cells translational …, 2022 - academic.oup.com
Adipose-derived stem or stromal cells (ASCs) possess promising potential in the fields of
tissue engineering and regenerative medicine due to their secretory activity, their …

Improving Schwann Cell Differentiation from Human Adipose Stem Cells with Metabolic Glycoengineering

J Du, Z Wang, X Liu, C Hu, KJ Yarema, X Jia - Cells, 2023 - mdpi.com
Schwann cells (SCs) are myelinating cells that promote peripheral nerve regeneration.
When nerve lesions form, SCs are destroyed, ultimately hindering nerve repair. The difficulty …

Bioengineering approaches for nerve graft revascularization: Current concepts and future directions

C Pereira, SV Lazar, A Wang - WIREs Mechanisms of Disease, 2023 - Wiley Online Library
Peripheral nerve injury (PNI) is the most common neurological injury in civilian and military
injuries, with over 360,000 PNI procedures performed in the US yearly. Segmental loss of …

Adipose tissue uses in peripheral nerve surgery

A Podsednik, R Cabrejo, J Rosen - International journal of molecular …, 2022 - mdpi.com
Currently, many different techniques exist for the surgical repair of peripheral nerves. The
degree of injury dictates the repair and, depending on the defect or injury of the peripheral …

[HTML][HTML] 人脂肪干细胞外泌体对糖尿病周围神经病变的作用及其机制

曹涛, 郝彤, 肖丹, 张伟锋, 计鹏… - 中华烧伤与创面 …, 2024 - zhsszz.xml-journal.net
目的探讨糖尿病周围神经病变(DPN) 中神经鞘胚素蛋白表达的变化及人脂肪干细胞(ADSC)
外泌体对神经鞘胚素蛋白表达变化的调节作用. 方法该研究为前瞻性观察性临床研究联合实验 …