Biomarkers play an essential role in the management of patients with invasive breast
cancer. For selecting patients likely to respond to endocrine therapy, both oestrogen …

Progesterone receptor (PR) is a master regulator in female reproductive tissues that controls
developmental processes and proliferation and differentiation during the reproductive cycle …

The response to endocrine therapy in breast cancer correlates with estrogen receptor (ER)
and progesterone receptor (PR) status. ER-positive/PR-negative breast cancers respond …

The majority of estrogen receptor (ER)-positive breast cancers are treated with endocrine
therapy. While this is effective, acquired resistance to therapies targeted against ER is a …

Pregnancy-associated breast cancer, which has a poor prognosis, is often overlooked by
clinicians and researchers alike. With the trend towards delayed child-bearing, an increase …

The ovarian hormones estrogen and progesterone are master regulators of the development
and function of a broad spectrum of human tissues, including the breast, reproductive and …

This review discusses mechanisms by which progesterone receptors (PR) regulate
transcription. We examine available data in different species and tissues regarding:(1) …

Purpose Response to endocrine therapy in breast cancer correlates with estrogen receptor
(ER) and progesterone receptor (PgR) status. It is usually easier to decide treatment …

Progesterone, the ovarian steroid hormone, regulates a plentitude of biological processes in
tissues ranging from the brain to bones. Recognizing the role of progesterone and its …

This paper reviews work on progesterone and the progesterone receptor (PR) in the mouse
mammary gland that has been used extensively as an experimental model. Studies have led …