2020 ESC Guidelines for the diagnosis and management of atrial fibrillation developed in collaboration with the European Association for Cardio-Thoracic Surgery …

G Hindricks, T Potpara, N Dagres, E Arbelo… - European heart …, 2021 - academic.oup.com
MicroRNAs (miRNAs) are small regulatory molecules post-transcriptionally suppressing
mRNA activity. Many miRNAs in various organisms have been cloned but many unknown …

Stroke–heart syndrome: recent advances and challenges

JF Scheitz, LA Sposato, J Schulz‐Menger… - Journal of the …, 2022 - Am Heart Assoc
After ischemic stroke, there is a significant burden of cardiovascular complications, both in
the acute and chronic phase. Severe adverse cardiac events occur in 10% to 20% of …

Atrial fibrillation detected after stroke and transient ischemic attack: a novel clinical concept challenging current views

LA Sposato, S Chaturvedi, CY Hsieh, CA Morillo… - Stroke, 2022 - Am Heart Assoc
Atrial fibrillation (AF) can be newly detected in approximately one-fourth of patients with
ischemic stroke and transient ischemic attack without previously recognized AF. We present …

Ischemic Stroke Risk in Patients With Nonvalvular Atrial Fibrillation: JACC Review Topic of the Week

M Alkhouli, PA Friedman - Journal of the American College of Cardiology, 2019 - jacc.org
The last decade has witnessed remarkable advances in pharmacological and
nonpharmacological strategies for stroke prevention in patients with atrial fibrillation …

Stroke prevention in nonvalvular atrial fibrillation: a stakeholder perspective

M Alkhouli, PA Noseworthy, CS Rihal… - Journal of the American …, 2018 - jacc.org
Ischemic stroke in patients with atrial fibrillation is associated with substantial morbidity and
mortality. The growing epidemic of atrial fibrillation worldwide has raised concerns about the …

Ischaemic stroke in anticoagulated patients with atrial fibrillation

C Stretz, TY Wu, D Wilson, DJ Seiffge… - Journal of Neurology …, 2021 - jnnp.bmj.com
Anticoagulation substantially reduces the risk of stroke in patients with atrial fibrillation (AF).
However, recent studies have shown that up to 22%–36% of patients on anticoagulation will …

Stroke and bleeding risk stratification in atrial fibrillation: a critical appraisal

DA Lane, GYH Lip - European Heart Journal Supplements, 2020 - academic.oup.com
Atrial fibrillation (AF) significantly increases the risk of stroke and, therefore, stroke
prevention is an essential component of the management for patients with AF. This requires …

Advances in the management of cardioembolic stroke associated with patent foramen ovale

B Mac Grory, EM Ohman, W Feng, Y Xian, S Yaghi… - bmj, 2022 - bmj.com
Patent foramen ovale (PFO) describes a valve in the interatrial septum that permits shunting
of blood or thrombotic material between the atria. PFOs are present in approximately 25% of …

Presence of left atrial fibrosis may contribute to aberrant hemodynamics and increased risk of stroke in atrial fibrillation patients

N Paliwal, RL Ali, M Salvador, R O'Hara, R Yu… - Frontiers in …, 2021 - frontiersin.org
Atrial fibrillation (AF) patients are at high risk of stroke, with the left atrial appendage (LAA)
found to be the most common site of clot formation. Presence of left atrial (LA) fibrosis has …

Anticoagulation timing in cardioembolic stroke and recurrent event risk

S Yaghi, T Trivedi, N Henninger, J Giles… - Annals of …, 2020 - Wiley Online Library
Objective Guidelines recommend initiating anticoagulation within 4 to 14 days after
cardioembolic stroke. Data supporting this did not account for key factors potentially affecting …