[HTML][HTML] On the chemical and biological characteristics of multifunctional compounds for the treatment of Parkinson's Disease

O García-Beltrán, PJ Urrutia, MT Núñez - Antioxidants, 2023 - mdpi.com
Protein aggregation, mitochondrial dysfunction, iron dyshomeostasis, increased oxidative
damage and inflammation are pathognomonic features of Parkinson's disease (PD) and …

[HTML][HTML] Liposome-Derived Nanosystems for the Treatment of Behavioral and Neurodegenerative Diseases: The Promise of Niosomes, Transfersomes, and …

PC Pires, AC Paiva-Santos, F Veiga - Pharmaceuticals, 2023 - mdpi.com
Psychiatric and neurodegenerative disorders are amongst the most prevalent and
debilitating diseases, but current treatments either have low success rates, greatly due to the …

[HTML][HTML] Inflammatory hallmarks in 6-OHDA-and LPS-induced Parkinson's disease in rats

Z Oliynyk, M Rudyk, T Dovbynchuk, N Dzubenko… - Brain, Behavior, & …, 2023 - Elsevier
Parkinson's disease (PD) is the second most common neurodegenerative disease, affecting
more than 1% of aged people. PD, which was previously identified as movement disorder …

Ginkgolide K delays the progression of osteoarthritis by regulating YAP to promote the formation of cartilage extracellular matrix

R Liu, Z Liu, H Chen, S He, S Wang… - Phytotherapy …, 2023 - Wiley Online Library
Osteoarthritis (OA) is a degenerative disease characterized by cartilage wear and
degradation. Ginkgolide K (GK) is a natural compound extracted from Ginkgo biloba leaves …

[HTML][HTML] Uncovering the pharmacology of Ginkgo biloba folium in the cell-type-specific targets of Parkinson's disease

YC Yan, ZH Xu, J Wang, WB Yu - Frontiers in Pharmacology, 2022 - frontiersin.org
Parkinson's disease (PD) is the second most common neurodegenerative disease with a
fast-growing prevalence. Developing disease-modifying therapies for PD remains an …

Mini-review:“ENTERIC GLIA FUNCTIONS IN NERVOUS TISSUE REPAIR: THERAPEUTIC TARGET OR TOOL?”

M Sunardi, C Cirillo - Neuroscience Letters, 2023 - Elsevier
In the body, nerve tissue is not only present in the central nervous system, but also in the
periphery. The enteric nervous system (ENS) is a highly organized intrinsic network of …

Pyruvate prevents dopaminergic neurodegeneration and motor deficits in the 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine model of Parkinson's disease

YM Kim, SY Choi, O Hwang, JY Lee - Molecular Neurobiology, 2022 - Springer
Parkinson's disease (PD) is a progressive neurodegenerative disorder characterized by the
selective loss of dopamine (DA) rgic neurons in the substantia nigra of the midbrain, and …

l-Borneol and d-Borneol promote transdifferentiation of astrocytes into neurons in rats by regulating Wnt/Notch pathway to exert neuroprotective effect during recovery …

R Ma, D Lu, Q Xie, J Yuan, M Ren, Y Li, J Wang, J Li… - Phytomedicine, 2023 - Elsevier
Abstract Background The Chinese medicines Borneolum and l-Borneolum have
neuroprotective effects on acute cerebral ischaemia–reperfusion (IR) in rats. Research on …

Therapeutic Potential of Natural Compounds from Herbs and Nutraceuticals in Alleviating Neurological Disorders: Targeting the Wnt Signaling Pathway

L Li, L Wang, L Zhang - Journal of Agricultural and Food …, 2024 - ACS Publications
As an important signaling pathway in multicellular eukaryotes, the Wnt signaling pathway
participates in a variety of physiological processes. Recent studies have confirmed that the …

[HTML][HTML] The Potential of Ginkgo biloba as a Source of Biologically Active Compounds—A Review of the Recent Literature and Patents

P Biernacka, I Adamska, K Felisiak - Molecules, 2023 - mdpi.com
Ginkgo biloba is a relict tree species showing high resistance to adverse biotic and abiotic
environmental factors. Its fruits and leaves have high medicinal value due to the presence of …