Proteomic profiling of urine: implications for lupus nephritis

N Aljaberi, M Bennett, HI Brunner… - Expert review of …, 2019 - Taylor & Francis
Introduction: Lupus nephritis (LN) is a common and significant manifestation, affecting 60%
of adults and 80% of children with systemic lupus erythematosus, with up to 30% of patients …

Non-invasive markers of ureteropelvic junction obstruction

S Decramer, JL Bascands, JP Schanstra - World journal of urology, 2007 - Springer
Non-invasive prognosis of the clinical progression of disease is of high interest, especially in
newborn and children. Neonatal ureteropelvic (UPJ) junction obstruction needs close and …

Urinary biomarkers in relapsing antineutrophil cytoplasmic antibody-associated vasculitis

JG Lieberthal, D Cuthbertson, S Carette… - The Journal of …, 2013 - jrheum.org
Objective. Glomerulonephritis (GN) is common in antineutrophil cytoplasmic antibody
(ANCA)-associated vasculitis (AAV), but tools for early detection of renal involvement are …

[HTML][HTML] Urinary peptides as potential non-invasive biomarkers for Lupus Nephritis: results of the Peptidu-LUP Study

M Tailliar, JP Schanstra, T Dierckx, B Breuil… - Journal of Clinical …, 2021 - mdpi.com
Background: Lupus nephritis (LN) is a severe manifestation of Systemic Lupus
Erythematosus (SLE). The therapeutic strategy relies on kidney biopsy (KB) results. We …

Recent progress in urinary proteomics

V Thongboonkerd - PROTEOMICS–Clinical Applications, 2007 - Wiley Online Library
Urinary proteomics has become one of the most attractive subdisciplines in clinical
proteomics as the urine is an ideal source for the discovery of noninvasive biomarkers for …

[HTML][HTML] Urine proteomes of healthy aging humans reveal extracellular matrix (ECM) alterations and immune system dysfunction

M Bakun, G Senatorski, T Rubel, A Lukasik… - Age, 2014 - Springer
Aging is a complex physiological process that poses considerable conundrums to rapidly
aging societies. For example, the risk of dying from cardiovascular diseases and/or cancer …

Urinary proteomics revealed prostaglandin H2D-isomerase, not Zn-α2-glycoprotein, as a biomarker for active lupus nephritis

P Somparn, N Hirankarn, A Leelahavanichkul… - Journal of …, 2012 - Elsevier
Although renal histopathology is the gold standard for the diagnosis and prognosis of lupus
nephritis (LN), the invasiveness of renal biopsy warrants the discovery of novel non-invasive …

The novel diagnostic biomarkers for focal segmental glomerulosclerosis

M Nafar, S Kalantari, S Samavat… - International journal …, 2014 - Wiley Online Library
Background. Focal segmental glomerulosclerosis (FSGS) is a glomerular injury with various
pathogenic mechanisms. Urine proteome panel might help in noninvasive diagnosis and …

MALDI-TOF MS combined with magnetic beads for detecting serum protein biomarkers and establishment of boosting decision tree model for diagnosis of systemic …

Z Huang, Y Shi, B Cai, L Wang, Y Wu, B Ying… - …, 2009 - academic.oup.com
Objectives. To discover novel potential biomarkers and establish a diagnostic pattern for
SLE by using proteomic technology. Methods. Serum proteomic spectra were generated by …

The applied basic research of systemic lupus erythematosus based on the biological omics

W Sui, X Hou, W Che, M Yang, Y Dai - Genes & Immunity, 2013 - nature.com
Systemic lupus erythematosus (SLE) is a systemic autoimmune disease characterized by
the production of autoantibodies directed against nuclear self-antigens and circulating …