Doxorubicin—an agent with multiple mechanisms of anticancer activity
Doxorubicin (DOX) constitutes the major constituent of anti-cancer treatment regimens
currently in clinical use. However, the precise mechanisms of DOX's action are not fully …
currently in clinical use. However, the precise mechanisms of DOX's action are not fully …
Liposomes in cancer therapy: how did we start and where are we now
MD Fulton, W Najahi-Missaoui - International Journal of Molecular …, 2023 - mdpi.com
Since their first discovery in the 1960s by Alec Bangham, liposomes have been shown to be
effective drug delivery systems for treating various cancers. Several liposome-based …
effective drug delivery systems for treating various cancers. Several liposome-based …
Multi‐functional liposome: a powerful theranostic nano‐platform enhancing photodynamic therapy
X Cheng, J Gao, Y Ding, Y Lu, Q Wei, D Cui… - Advanced …, 2021 - Wiley Online Library
Although photodynamic therapy (PDT) has promising advantages in almost non‐invasion,
low drug resistance, and low dark toxicity, it still suffers from limitations in the lipophilic …
low drug resistance, and low dark toxicity, it still suffers from limitations in the lipophilic …
Lipid-based drug delivery systems in cancer therapy: what is available and what is yet to come
P Yingchoncharoen, DS Kalinowski… - Pharmacological …, 2016 - ASPET
Cancer is a leading cause of death in many countries around the world. However, the
efficacy of current standard treatments for a variety of cancers is suboptimal. First, most …
efficacy of current standard treatments for a variety of cancers is suboptimal. First, most …
Surface modification strategies in translocating nano-vesicles across different barriers and the role of bio-vesicles in improving anticancer therapy
Nanovesicles and bio-vesicles (BVs) have emerged as promising tools to achieve targeted
cancer therapy due to their ability to overcome many of the key challenges currently being …
cancer therapy due to their ability to overcome many of the key challenges currently being …
Antibody fragments as nanoparticle targeting ligands: a step in the right direction
Recent advances in nanomedicine have shown that dramatic improvements in nanoparticle
therapeutics and diagnostics can be achieved through the use of disease specific targeting …
therapeutics and diagnostics can be achieved through the use of disease specific targeting …
Ligand-targeted liposome design: challenges and fundamental considerations
GT Noble, JF Stefanick, JD Ashley, T Kiziltepe… - Trends in …, 2014 - cell.com
Nanomedicine, particularly liposomal drug delivery, has expanded considerably over the
past few decades, and several liposomal drugs are already providing improved clinical …
past few decades, and several liposomal drugs are already providing improved clinical …
In Vivo Biomolecule Corona around Blood-Circulating, Clinically Used and Antibody-Targeted Lipid Bilayer Nanoscale Vesicles
The adsorption of proteins and their layering onto nanoparticle surfaces has been called the
“protein corona”. This dynamic process of protein adsorption has been extensively studied …
“protein corona”. This dynamic process of protein adsorption has been extensively studied …
Strategies for the intracellular delivery of nanoparticles
The ability to target contrast agents and therapeutics inside cells is becoming important as
we strive to decipher the complex network of events that occur within living cells and design …
we strive to decipher the complex network of events that occur within living cells and design …
Active targeting schemes for nanoparticle systems in cancer therapeutics
JD Byrne, T Betancourt, L Brannon-Peppas - Advanced drug delivery …, 2008 - Elsevier
The objective of this review is to outline current major cancer targets for nanoparticle
systems and give insight into the direction of the field. The major targeting strategies that …
systems and give insight into the direction of the field. The major targeting strategies that …