[HTML][HTML] Head and neck squamous cell carcinoma

DE Johnson, B Burtness, CR Leemans… - Nature reviews Disease …, 2020 - nature.com
Most head and neck cancers are derived from the mucosal epithelium in the oral cavity,
pharynx and larynx and are known collectively as head and neck squamous cell carcinoma …

Treating head and neck cancer in the age of immunotherapy: a 2023 update

A Bhatia, B Burtness - Drugs, 2023 - Springer
Most patients diagnosed with head and neck squamous cell carcinoma (HNSCC) will
present with locally advanced disease, requiring multimodality therapy. While this approach …

Management of salivary gland malignancy: ASCO guideline

JL Geiger, N Ismaila, B Beadle, JJ Caudell… - Journal of Clinical …, 2021 - ascopubs.org
PURPOSE To provide evidence-based recommendations for practicing physicians and
other healthcare providers on the management of salivary gland malignancy. METHODS …

[HTML][HTML] Elective nodal irradiation mitigates local and systemic immunity generated by combination radiation and immunotherapy in head and neck tumors

LB Darragh, J Gadwa, TT Pham, B Van Court… - Nature …, 2022 - nature.com
In the setting of conventional radiation therapy, even when combined with immunotherapy,
head and neck cancer often recurs locally and regionally. Elective nodal irradiation (ENI) is …

Meta-analysis of chemotherapy in head and neck cancer (MACH-NC): An update on 107 randomized trials and 19,805 patients, on behalf of MACH-NC Group

B Lacas, A Carmel, C Landais, SJ Wong… - Radiotherapy and …, 2021 - Elsevier
Abstract Background and purpose The Meta-Analysis of Chemotherapy in squamous cell
Head and Neck Cancer (MACH-NC) demonstrated that concomitant chemotherapy (CT) …

Low-dose immunotherapy in head and neck cancer: a randomized study

VM Patil, V Noronha, N Menon, R Rai… - Journal of Clinical …, 2023 - ascopubs.org
PURPOSE The regimens approved for the treatment of advanced head and neck squamous
cell carcinoma are accessible to only 1%-3% of patients in low-and middle-income countries …

[HTML][HTML] A phase I/Ib trial and biological correlate analysis of neoadjuvant SBRT with single-dose durvalumab in HPV-unrelated locally advanced HNSCC

LB Darragh, MM Knitz, J Hu, ET Clambey, J Backus… - Nature Cancer, 2022 - nature.com
Five-year survival for human papilloma virus-unrelated head and neck squamous cell
carcinomas remain below 50%. We assessed the safety of administering combination …

[HTML][HTML] Immunotherapy for head and neck cancer: Present and future

M Fasano, CM Della Corte, R Di Liello… - Critical reviews in …, 2022 - Elsevier
Immunotherapy has changed the treatment landscape of Head and Neck cancer (HNC).
Different immune checkpoint inhibitors targeting PD-1/PD-L1 axis have been approved for …

[HTML][HTML] Recent advances and future directions in clinical management of head and neck squamous cell carcinoma

J Muzaffar, S Bari, K Kirtane, CH Chung - Cancers, 2021 - mdpi.com
Simple Summary Even with recent advances, there are urgent needs for novel therapies to
improve overall survival and decrease toxicities in the management of head and neck …

A multi-omics machine learning framework in predicting the survival of colorectal cancer patients

M Yang, H Yang, L Ji, X Hu, G Tian, B Wang… - Computers in biology and …, 2022 - Elsevier
Background Colorectal cancer (CRC), the 3rd most universal cancer globally, accounts for
approximately 10% of newly diagnosed cancer incidences each year. Identifying biomarkers …