Mortality from colorectal cancer is reduced through screening and early detection; moreover,
removal of neoplastic lesions can reduce cancer incidence. While understanding of the risk …

Colorectal cancer (CRC) results from the progressive accumulation of multiple genetic and
epigenetic aberrations within cells. The progression from colorectal adenoma to carcinoma …

Roughly 50% of cancer cases occur in people aged 65 years or older. Older people are
often diagnosed at a later stage and might receive less (intensive) treatment, which might …

The electrical current blockade of a peptide or protein threading through a nanopore can be
used as a fingerprint of the molecule in biosensor applications. However, threading of full …

Colorectal cancer (CRC) is the third most frequently detected type of cancer, and the second
most common cause of cancer‑related mortality globally. The American Cancer Society …

Colorectal cancer is a complex disease resulting from somatic genetic and epigenetic
alterations, including locus-specific CpG island methylation and global DNA or LINE-1 …

Molecular classification of colorectal cancer is evolving. As our understanding of colorectal
carcinogenesis improves, we are incorporating new knowledge into the classification …

Background & Aims: Sporadic colorectal cancers with a high degree of microsatellite
instability are a clinically distinct subgroup with a high incidence of BRAF mutation and are …

Colorectal cancer is a heterogeneous disease. There are three main pathways to colorectal
cancer: the chromosomal instability pathway, the CpG island methylator phenotype pathway …

Colorectal cancer (CRC) ranks among the three most common cancers in terms of both
cancer incidence and cancer‐related deaths in most Western countries. Serrated …