Target-based drug discovery is the dominant paradigm of drug discovery; however, a
comprehensive evaluation of its real-world efficiency is lacking. Here, a manual systematic …

Evidence has been accumulating that, in men, some of the biological actions traditionally
attributed to testosterone acting via the androgen receptor may in fact be dependent on its …

Estrogen plays a prominent role in regulating and coordinating energy homeostasis
throughout the growth, development, reproduction, and aging of women. Estrogen receptors …

Steroid hormones are capable of diffusing through cell membranes to bind with intracellular
receptors to regulate numerous physiological processes. Three classes of steroid hormones …

Lifestyle health has been recognized as an evidence-based innovation that defines how
everyday behaviors and routines influence the avoidance and therapy of illness and …

Benign prostatic hyperplasia (BPH) is an age-related disorder, which is one of the most
prevalent and costly benign neoplasms in men with over 94 million cases worldwide …

Emerging scientific advances in microbial research linking estrogens and the gut-skin
microbiome in reference to dermal health are featured in this narrative review of journal …

The narrative for this overview focuses on updating the factors that influence skin aging and
the important role estrogens and selective estrogen receptor modulators (SERMs) play in …

Postmenopausal, obese women have a significantly higher risk of developing estrogen
receptor-positive (ER+) breast tumors, that are resistant to therapies and are associated with …

Androstenedione (ADSD) was the main androgen detected in wastewaters. Chlorella was
the most widely used plant in biological wastewater treatment process. In order to …