Tetracyclines possess many properties considered ideal for antibiotic drugs, including
activity against Gram-positive and-negative pathogens, proven clinical safety, acceptable …

Tigecycline is unique glycylcycline class of semisynthetic antimicrobial agents developed for
the treatment of polymicrobial infections caused by multidrug-resistant Gram-positive and …

The molecular epidemiology and mechanisms of resistance of carbapenem-resistant
Enterobacteriaceae (CRE) were determined in hospitals in the countries of the Gulf …

Infections due to Gram-negative bacilli (GNB) are a leading cause of morbidity and mortality
worldwide. The extent of antibiotic resistance in GNB in countries of the Gulf Cooperation …

Tigecycline (TIG) exhibits broad-spectrum activity against many Gram-positive and Gram-
negative pathogens. However, clinical resistance has emerged recently and has been …

Infections due to carbapenem-resistant Klebsiella pneumoniae (CR-KP) have emerged as a
public health problem worldwide given their spread dynamics and the limited therapeutic …

During the past decades, rates of multidrug-resistant (MDR) and carbapenem-resistant (CR)
Enterobacteriaceae clinical isolates, mainly Klebsiella spp., Escherichia coli, Enterobacter …

To establish the role of local transmission versus possible pathogen import due to previous
foreign exposure in infections caused by carbapenem non-susceptible Enterobacteriaceae …

Background The increasing and rapid spread of metallo-beta-lactamase (MBL) producing
Enterobacteriaceae, particularly Escherichia coli and Klebsiella pneumoniae represents an …

We characterized the molecular basis of carbapenemase production in carbapenem-
resistant Gram-negative bacteria isolated from hospitalized patients from Saudi Arabia in the …