Primary lung cancer is one of the most common malignant tumors in China. Approximately
60% of lung cancer patients have distant metastasis at the initial diagnosis, so it is …

Lung cancer (LC) is the main cause of cancer-related mortality. Most LC patients are
diagnosed in an advanced stage when the symptoms are obvious, and the prognosis is …

In the last years, liquid biopsy gained increasing clinical relevance for detecting and
monitoring several cancer types, being minimally invasive, highly informative and replicable …

DNA methylation is an epigenetic mechanism that is related to mammalian cellular
differentiation, gene expression regulation, and disease. In several studies, DNA …

Bladder cancer (BC) is a clinical challenge worldwide with late clinical presentation, poor
prognosis, and low survival rates. Traditional cystoscopy and tissue biopsy are routine …

The lung microbiome plays an essential role in maintaining healthy lung function, including
host immune homeostasis. Lung microbial dysbiosis or disruption of the gut-lung axis can …

Over the past decade, the detection and analysis of liquid biopsy biomarkers such as
circulating tumor cells (CTCs) and circulating tumor DNA (ctDNA) have advanced …

The role of epigenetics in the etiology of cancer progression is being emphasized for the
past two decades to check the impact of chromatin modifiers and remodelers. Histone …

Despite efforts to improve earlier diagnosis of non-small cell lung cancer (NSCLC), most
patients present with advanced stage disease, which is often associated with poor survival …

Circulating tumor cells (CTCs) play a pivotal role in metastasis, the leading cause of cancer-
associated death. Recent improvements of CTC isolation tools, coupled with a steady …