Ovarian cancer represents one of the most aggressive female tumors worldwide. Over the
decades, the therapeutic options for the treatment of ovarian cancer have been improved …

Long-standing scarcity of efficacious treatments and tumor heterogeneity have contributed to
triple-negative breast cancer (TNBC), a subtype with a poor prognosis and aggressive …

Background Exposure to ambient particulate air pollution contributes substantially to the
mortality and morbidity due to cardiovascular diseases (CVD), respiratory diseases and …

Thymoquinone (TQ), the bioactive constituent of Nigella Sativa seeds, is a well-known
natural compound for the management of several types of cancers. The anti-cancer …

The last 10 years witnessed an acceleration of our understanding of what genetic factors
underpin the risk of breast cancer. Rare high-and moderate-penetrance variants such as …

Background There is an increasing amount of data from Latin America on the
characterization of BRCA variants; however, there is limited information from Peru. We …

Background Childhood cancer has a poorly known etiology, and investigating the
underlying genetic background may provide novel insights. A recognized association exists …

Breast cancer (BC) is one of the most common cancers among women; genetic mutations
reflect the development of this disease. Mutations in cell signaling factors can be the main …

Simple Summary Neoantigens are novel proteins presented on the cell surface and derived
from the accumulation of somatic mutations in tumor cells. They can be recognized by the …

Cancer is a genomic disease, with driver mutations contributing to tumorigenesis. These
potentially heritable variants influence risk and underlie familial breast cancer (BC). This …