Owing to their unique chemical and physical properties, hydrogels are attracting increasing
attention in both basic and translational biomedical studies. Although the classical hydrogels …

Abstract Three-dimensional (3D) stem cell culture systems have attracted considerable
attention as a way to better mimic the complex interactions between individual cells and the …

Three-dimensional cell and organoid cultures rely on the mechanical support of viscoelastic
matrices. However, commonly used matrix materials lack control over key cell-instructive …

Hydrogels are highly water-swollen molecular networks that are ideal platforms to create
tissue mimetics owing to their vast and tunable properties. As such, hydrogels are promising …

Organoids are in vitro model systems that mimic the complexity of organs with multicellular
structures and functions, which provide great potential for biomedical and tissue …

Recent advances in 3D cell culture technology have enabled scientists to generate stem cell
derived organoids that recapitulate the structural and functional characteristics of native …

Gelatin is a widely utilized bioprinting biomaterial due to its cell‐adhesive and enzymatically
cleavable properties, which improve cell adhesion and growth. Gelatin is often covalently …

Recent advances in materials science and engineering highlight the importance of
designing sophisticated biomaterials with well-defined architectures and tunable properties …

The restricted porosity of most hydrogels established for in vitro 3D tissue engineering
applications limits embedded cells with regard to their physiological spreading, proliferation …

The extracellular matrix plays a critical role in bioinstructing cellular self‐assembly and
spatial (re) configuration processes that culminate in human organoids in vitro generation …