Tumor development and progression require chemical and mechanical cues derived from
cellular and non-cellular components in the tumor microenvironment, including the …

Cancer metabolism is an essential aspect of tumorigenesis, as cancer cells have increased
energy requirements in comparison to normal cells. Thus, an enhanced metabolism is …

The ever-increasing incidence of obesity and related disorders impose serious challenges
on public health worldwide. Brown adipose tissue (BAT) has strong capacity for promoting …

Dysregulated physical stresses are generated during tumorigenesis that affect the
surrounding compliant tissues including adipocytes. However, the effect of physical …

Obesity is a strong risk factor for cancer progression, posing obesity-related cancer as one of
the leading causes of death. Nevertheless, the molecular mechanisms that endow cancer …

Non-alcoholic fatty liver disease (NAFLD) is the most common chronic liver disease
worldwide. Much of the recognised health-care burden occurs in the minority of people with …

Obesity is a metabolic condition usually accompanied by insulin resistance (IR), type 2
diabetes (T2D), and dyslipidaemia, which is characterised by excessive fat accumulation …

Simple Summary A major challenge in treating cancer is when the cancer spreads from its
original site to other parts of the body, a process also known as metastasis. In order to …

The tumour microenvironment (TME) plays a pivotal role in tumour fate determination. The
TME acts together with the genetic material of tumour cells to determine their initiation …

Morning chronotype has been associated with a reduced risk of prostate and breast cancer.
However, few studies have examined whether chronotype is associated with digestive tract …