WNT-signaling controls important cellular processes throughout embryonic development
and adult life, so any deregulation of this signaling can result in a wide range of pathologies …

The development and progression of melanoma have been attributed to independent or
combined genetic and epigenetic events. There has been remarkable progress in …

Neurodegenerative disorders are significantly increasing in incidence as the age of the
global population continues to climb with improved life expectancy. At present, more than 30 …

Long non-coding RNAs (lncRNAs) are involved in tumorigenesis. Metastasis-associated
lung adenocarcinoma transcript 1 (MALAT1), an lncRNAs, is associated with the growth and …

Long intergenic nonprotein coding RNA 518 (LINC00518) has been shown to promote
cancer cell growth and metastasis in some human tumors. Although it has been reported …

Cutaneous melanoma is an aggressive tumor; its incidence has been reported to increase
fast in the past decades. Melanoma is a heterogeneous tumor, with most patients harboring …

Malignant melanoma is the most lethal type of skin cancer with high rates of mortality.
Although current treatment options provide a short-clinical benefit, acquired-drug resistance …

As a proliferative and restorative entity, Wnt1 inducible signaling pathway protein 1 (WISP1)
is emerging as a novel target for a number of therapeutic strategies that are relevant for …

Diabetes mellitus affects almost 350 million individuals throughout the globe resulting in
significant morbidity and mortality. Of further concern is the growing population of individuals …

Abstract HOX transcript antisense RNA (HOTAIR) is associated with the growth and
metastasis of many human tumors, but its biological roles in malignant melanoma remain …