Angiogenesis is a crucial process for tissue development, repair, and tumor survival.
Vascular endothelial growth factor (VEGF) is a key driver secreted by cancer cells …

Small-cell lung cancer (SCLC) cases represent approximately 15% of all lung cancer cases,
remaining a recalcitrant malignancy with poor survival and few treatment options. In the last …

Lactic acidosis characterizes the tumor microenvironment (TME) and is involved in the
mechanisms leading to cancer progression and dissemination through the reprogramming …

Background: Lung cancer has a high incidence and mortality rate worldwide. Vasculogenic
mimicry (VM) is a specific modality of tumor angiogenesis that could potentially be a new …

We describe the development and validation of an HPLC-MS/MS method to assess the
pharmacokinetics and tumour distribution of ZST316, an arginine analogue with inhibitory …

Tumor growth depends on the vascular system, either through the expansion of blood
vessels or novel adaptation by tumor cells. One of these novel pathways is vasculogenic …

Intervertebral disk degeneration (IDD) is a chronic inflammatory disease with intricate
connections between immune infiltration and oxidative stress (OS). Complex cell niches …

Introduction Vasculogenic mimicry (VM) alludes to the ability of cancer cells to organize on
three-dimensional channel-like structures to obtain nutrients and oxygen. This mechanism …

Background Vasculogenic Mimicry (VM) can reduce the efficacy of anti-angiogenesis and
promote distant metastasis in hepatocellular carcinoma (HCC). Our previous studies have …

Exosomes derived from mesenchymal stem cells (MSC-Exos) are nano-sized extracellular
vesicles enriched with bioactive molecules, such as microRNAs, enzymes, cytokines …