Gene body methylation in cancer: molecular mechanisms and clinical applications
Q Wang, F Xiong, G Wu, W Liu, J Chen, B Wang… - Clinical …, 2022 - Springer
DNA methylation is an important epigenetic mechanism that regulates gene expression. To
date, most DNA methylation studies have focussed on CpG islands in the gene promoter …
date, most DNA methylation studies have focussed on CpG islands in the gene promoter …
Mobile DNA in health and disease
HH Kazazian Jr, JV Moran - New England Journal of Medicine, 2017 - Mass Medical Soc
Mobile DNA in Health and Disease | New England Journal of Medicine Skip to main content
Access provided byMGH The New England Journal of Medicine homepage Advanced Search …
Access provided byMGH The New England Journal of Medicine homepage Advanced Search …
Dynamics of genome size evolution in birds and mammals
A Kapusta, A Suh, C Feschotte - Proceedings of the …, 2017 - National Acad Sciences
Genome size in mammals and birds shows remarkably little interspecific variation compared
with other taxa. However, genome sequencing has revealed that many mammal and bird …
with other taxa. However, genome sequencing has revealed that many mammal and bird …
Losing DNA methylation at repetitive elements and breaking bad
XG Pappalardo, V Barra - Epigenetics & chromatin, 2021 - Springer
Background DNA methylation is an epigenetic chromatin mark that allows heterochromatin
formation and gene silencing. It has a fundamental role in preserving genome stability …
formation and gene silencing. It has a fundamental role in preserving genome stability …
Coevolution between transposable elements and recombination
One of the most striking patterns of genome structure is the tight, typically negative,
association between transposable elements (TEs) and meiotic recombination rates. While …
association between transposable elements (TEs) and meiotic recombination rates. While …
The impact of retrotransposons on human genome evolution
R Cordaux, MA Batzer - Nature reviews genetics, 2009 - nature.com
Their ability to move within genomes gives transposable elements an intrinsic propensity to
affect genome evolution. Non-long terminal repeat (LTR) retrotransposons—including LINE …
affect genome evolution. Non-long terminal repeat (LTR) retrotransposons—including LINE …
Origins and functional impact of copy number variation in the human genome
Structural variations of DNA greater than 1 kilobase in size account for most bases that vary
among human genomes, but are still relatively under-ascertained. Here we use tiling …
among human genomes, but are still relatively under-ascertained. Here we use tiling …
Alu elements: know the SINEs
P Deininger - Genome biology, 2011 - Springer
Alu elements: know the SINEs | Genome Biology Skip to main content SpringerLink Account
Menu Find a journal Publish with us Track your research Search Cart 1.Home 2.Genome …
Menu Find a journal Publish with us Track your research Search Cart 1.Home 2.Genome …
Active human retrotransposons: variation and disease
DC Hancks, HH Kazazian Jr - Current opinion in genetics & development, 2012 - Elsevier
Mobile DNAs, also known as transposons or 'jumping genes', are widespread in nature and
comprise an estimated 45% of the human genome. Transposons are divided into two …
comprise an estimated 45% of the human genome. Transposons are divided into two …